A Research Study on How Well Semaglutide Works in Adolescents With Overweight or Obesity
Public ClinicalTrials.gov record NCT04102189. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Effect and Safety of Semaglutide 2.4 mg Once Weekly on Weight Management in Adolescents With Overweight or Obesity
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will look at the change in teenagers' body weight from the start to the end of the study. This is to compare the effect on body weight in teenagers taking semaglutide (a new medicine) and teenagers taking "dummy" medicine. The teenagers in the study and their parents will also have talks with study staff about healthy food choices, how to be more physically active and what they can do to help the teenagers lose weight. The teenagers will either get semaglutide or "dummy" medicine - which treatment is decided by chance. The teenagers will take 1 injection every week, on the same day of the week for about 15 months. The study medicine is injected with a thin needle in a skin fold in the stomach, thigh or upper arm. The teenagers will have 17 clinic visits, will have blood samples taken and will have to complete questionnaires and keep a diary. All this will be explained before study start.
Study identification
- NCT ID
- NCT04102189
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 201 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 17 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 6, 2019
- Primary completion
- Mar 24, 2022
- Completion
- Mar 27, 2022
- Last update posted
- Dec 10, 2025
2019 – 2022
United States locations
- U.S. sites
- 23
- U.S. states
- 16
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Children's Hospital Los Angeles - Endocrinology | Los Angeles | California | 90027 | — |
| Solaris Clinical Research | Meridian | Idaho | 83646 | — |
| Pennington Biomed Res Ctr | Baton Rouge | Louisiana | 70808-4124 | — |
| DelRicht Research | Gretna | Louisiana | 70053 | — |
| Barry J. Reiner, MD LLC | Baltimore | Maryland | 21229 | — |
| Massachusetts General Hospital_Cary | Boston | Massachusetts | 02114-2621 | — |
| University of Minnesota_CPOM | Minneapolis | Minnesota | 55414 | — |
| University of Minnesota_Minneapolis | Minneapolis | Minnesota | 55455 | — |
| UBMD Peds-Div of Endo/Diabetes | Buffalo | New York | 14203 | — |
| WakeMed Childn Endo-Dbt_Raleig | Raleigh | North Carolina | 27610 | — |
| Valley Weight Loss Clinic | Fargo | North Dakota | 58104 | — |
| Aventiv Research Inc | Columbus | Ohio | 43213 | — |
| PriMed Clinical Research | Dayton | Ohio | 45419 | — |
| Geisinger Clinic | Danville | Pennsylvania | 17822-2111 | — |
| Children's Hosptl Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| UPMC Child Hosp-Pittsburgh | Pittsburgh | Pennsylvania | 15224 | — |
| Medical Research South, LLC_Cary | Goose Creek | South Carolina | 29445 | — |
| Greenville Hospital System Pediatric Endo | Greenville | South Carolina | 29615 | — |
| Monument Health Clinical Rsrch | Rapid City | South Dakota | 57701 | — |
| Discovery MM Services, Inc | Houston | Texas | 77061 | — |
| Univ Of Texas Hlth Science Cntr | San Antonio | Texas | 78229 | — |
| National Clin Res Inc. | Richmond | Virginia | 23294 | — |
| Marshfield Clinic | Marshfield | Wisconsin | 54449 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 28 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04102189, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 10, 2025 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04102189 live on ClinicalTrials.gov.