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Completed Phase 3 Interventional

Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis

ClinicalTrials.gov ID: NCT04102371

Public ClinicalTrials.gov record NCT04102371. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 16, 2026, 9:13 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Study identification

NCT ID
NCT04102371
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Children's Hospital of Philadelphia
Other
Enrollment
9,041 participants

Conditions and interventions

Conditions

Interventions

  • Lactated Ringer Drug
  • Normal Saline Drug
  • Plasma-lyte Drug

Drug

Eligibility (public fields only)

Age range
2 Months to 17 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 24, 2020
Primary completion
Nov 30, 2025
Completion
Jan 30, 2026
Last update posted
Mar 4, 2026

2020 – 2026

United States locations

U.S. sites
22
U.S. states
16
U.S. cities
22
Facility City State ZIP Site status
UC Davis: University of California, Davis Davis California 95616
CHLA: Children's Hospital Los Angeles Los Angeles California 90027
UCSF Benioff Children's Hospital San Francisco California 94143
Children's Colorado: University of Colorado Denver Colorado 80204
Children's Hospital of Atlanta Emory Georgia 30322
Lurie Children's: Ann & Robert H. Lurie Children's Hospital of Chicago Chicago Illinois 60611
Boston Children's Hospital Boston Massachusetts 02115
CS Mott Children's Hospital Ann Arbor Michigan 48109
Washington University St Louis Missouri 63130
Columbia: New York-Presbyterian Hospital New York New York 10065-4870
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229
Nationwide Children's Hospital Columbus Ohio 43205
The Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104
Children's Hospital of Pittsburgh Pittsburgh Pennsylvania 15224
Hasbro Children's Hospital Providence Rhode Island 02903
Dallas Children's: Children's Medical Center Dallas/UT southwestern Dallas Texas 75235
Texas Children's Hospital Houston Texas 77030
Primary Children's: University of Utah Salt Lake City Utah 84113
Children's Hospital of Richmond at VCU Richmond Virginia 23284
Children's National Medical Center Columbia Washington 20010
Seattle Children's Hospital Seattle Washington 98105
Milwaukee (MCW): Medical College of Wisconsin Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04102371, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 4, 2026 · Synced May 16, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04102371 live on ClinicalTrials.gov.

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