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Completed Phase 2 Interventional

A Study to Compare FCD105 Foam to Minocycline 3% Foam, Adapalene 0.3% Foam and Vehicle Foam.

ClinicalTrials.gov ID: NCT04104685

Public ClinicalTrials.gov record NCT04104685. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 8:17 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Prospective, Multicenter, Randomized, Double-Blind, Vehicle-Controlled Phase 2 Study to Evaluate the Safety and Efficacy of a Combination of 3% Minocycline and 0.3% Adapalene Topical Foam Formulation for the Treatment of Moderate-to-Severe Acne (Study FX2016 40)

Study identification

NCT ID
NCT04104685
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Vyne Therapeutics Inc.
Industry
Enrollment
446 participants

Conditions and interventions

Conditions

Interventions

  • 0.3% Adapalene Foam Drug
  • 3% Minocycline Foam Drug
  • FCD105 Combination Product
  • Vehicle Foam Other

Drug · Combination Product · Other

Eligibility (public fields only)

Age range
12 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 17, 2019
Primary completion
Feb 27, 2020
Completion
Mar 2, 2020
Last update posted
Feb 4, 2021

2019 – 2020

United States locations

U.S. sites
35
U.S. states
18
U.S. cities
35
Facility City State ZIP Site status
Foamix Institution #134 Bryant Arkansas 72022
Foamix Institution #121 Rogers Arkansas 72758
Foamix Institution #106 Encino California 91436
Foamix Institution #103 Fremont California 94538
Foamix Institution #122 Huntington Beach California 92647
Foamix Institution #109 Manhattan Beach California 90266
Foamix Institution #132 San Diego California 92123
Foamix Institution #107 Hialeah Florida 33016
Foamix Institution #127 Lake City Florida 32055
Foamix Institution #101 Miami Florida 33126
Foamix Institution #135 Miami Beach Florida 33162
Foamix Institution #118 Sanford Florida 32771
Foamix Institution #120 Sunrise Florida 33351
Foamix Institution #128 Tampa Florida 33607
Foamix Institution #130 New Albany Indiana 47150
Foamix Institution #116 Plainfield Indiana 46168
Foamix Institution #123 Louisville Kentucky 40241
Foamix Institution #126 Baton Rouge Louisiana 70809
Foamix Institution #124 New Orleans Louisiana 70115
Foamix Institution #136 Watertown Massachusetts 02472
Foamix Institution #114 Clinton Township Michigan 48038
Foamix Institution #111 Fridley Minnesota 55432
Foamix Institution #102 Las Vegas Nevada 89148
Foamix Institution #115 New York New York 10022
Foamix Institution #108 Stony Brook New York 11790
Foamix Institution #104 High Point North Carolina 27262
Foamix Institution #133 Gresham Oregon 97030
Foamix Institution #125 Johnston Rhode Island 02919
Foamix Institution #119 Mt. Pleasant South Carolina 29464
Foamix Institution #110 Arlington Texas 76011
Foamix Institution #117 College Station Texas 77845
Foamix Institution #112 Pflugerville Texas 78660
Foamix Institution #105 San Antonio Texas 78213
Foamix Institution #131 Layton Utah 84041
Foamix Institution #113 Spokane Washington 99202

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04104685, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 4, 2021 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04104685 live on ClinicalTrials.gov.

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