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Completed Phase 2 Interventional Results available

Evaluation of S-600918 in Adults With Refractory Chronic Cough

ClinicalTrials.gov ID: NCT04110054

Public ClinicalTrials.gov record NCT04110054. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 20, 2026, 11:52 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2b, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Dose-selection Study of S-600918 in Patients With Refractory Chronic Cough

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary objective of this study is to determine the optimal dose of S-600918 in patients with refractory chronic cough by evaluating the change from baseline in 24-hour cough frequency (coughs per hour) with S-600918 compared with placebo.

Study identification

NCT ID
NCT04110054
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Shionogi
Industry
Enrollment
406 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 13, 2020 (Actual)
Primary completion
Dec 8, 2020 (Actual)
Completion
Dec 28, 2020 (Actual)
Last update posted
Mar 27, 2024

2020

United States locations

U.S. sites
51
U.S. states
23
U.S. cities
43
Facility City State ZIP Site status
Research Solutions of Arizona Litchfield Park Arizona 85340 —
Pulmonary Associates, PA Phoenix Arizona 85032 —
Alliance for Multispecialty Research Tempe Arizona 85283 —
Southern California Institute For Respiratory Diseases, Inc. Los Angeles California 90048 —
Allergy & Asthma Associates of Southern California dba Southern California Research Mission Viejo California 92691 —
California Medical Research Associates, Inc. Northridge California 91324 —
Center for Clinical Trials, LLC Paramount California 90723 —
Institute of HealthCare Assessment, Inc. San Diego California 92120 —
Sher Allergy Specialist/Center for Cough Largo Florida 33778 —
Medical Research Of Central Florida, LLC Leesburg Florida 34748 —
Lenus Research & Medical Group, LLC Sweetwater Florida 33172 —
Rush University Medical Center Chicago Illinois 60612 —
Sneeze, Wheeze, & Itch Associates, LLC Normal Illinois 61761 —
University of Kansas Medical Center-Hospital Kansas City Kansas 66160 —
University of Kansas Medical Center Kansas City Kansas 66160 —
Abraham Research PLLC Fort Mitchell Kentucky 41017 —
Shionogi Research Site Bangor Maine 04401 —
St. Joseph's Hospital Bangor Maine 04401 —
Minnesota Lung Center Edina Minnesota 55435 —
Mayo Clinic Pulmonary Clinical Research Unit Rochester Minnesota 55905 —
Mayo Clinic, Division of Pulmonary and Critical Care Medicine Rochester Minnesota 55905 —
Minnesota Lung Center Woodbury Minnesota 55125 —
University of Missouri Hospital and Clinics, ENT & Allergy Center of Missouri Columbia Missouri 65201 —
University of Missouri Hospital and Clinics, Hearing and Balance Center Columbia Missouri 65201 —
University of Missouri Hospital - Clinical Research Center Columbia Missouri 65212 —
Clayton Sleep Institute, LLC St Louis Missouri 63123 —
Associated Specialists in Medicine, PC St Louis Missouri 63141 —
The Clinical Research Center, LLC St Louis Missouri 63141 —
Montana Medical Research, Inc. Missoula Montana 59808 —
Creighton University Clinical Research Office Omaha Nebraska 68124 —
Atlantic Research Center, LLC Ocean City New Jersey 07712 —
Montefiore Medical Center The Bronx New York 10461 —
American Health Research Inc Charlotte North Carolina 28207 —
Clinical Research of Gastonia Gastonia North Carolina 28504 —
Southeastern Research Center Winston-Salem North Carolina 27103 —
New Horizons Clinical Research Cincinnati Ohio 45242 —
Cleveland Clinic Foundation Cleveland Ohio 44195 —
Northwest Research Center Portland Oregon 97202 —
Clinical Research Associates of Central PA, LLC DuBois Pennsylvania 15801 —
AAPRI Clinical Research Institute Warwick Rhode Island 02886 —
ADAC Research, PA Greenville South Carolina 29607 —
Clinical Research of Rock Hill Rock Hill South Carolina 29732 —
Pharmaceutical Research & Consulting, Inc Dallas Texas 75231 —
MCA Research Houston Texas 77084 —
Metroplex Pulmonary and Sleep Center McKinney Texas 75069 —
Diagnostics Research Group San Antonio Texas 78229 —
Allergy and Asthma Care of Waco Waco Texas 76712 —
Allergy Asthma Research Institute Waco Texas 76712 —
Intermountain Clinical Research Draper Utah 84020 —
Tidewater Physicians Multispecialty Group Clinical Research Williamsburg Virginia 23188 —
Allergy, Asthma & Sinus Center, S.C. Greenfield Wisconsin 53228 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 85 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04110054, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 27, 2024 · Synced Oct 20, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04110054 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →