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Completed Phase 2 Interventional Results available

Linaclotide Safety and Efficacy in 2 to 5-Year-Old Participants With Functional Constipation

ClinicalTrials.gov ID: NCT04110145

Public ClinicalTrials.gov record NCT04110145. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 2:33 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Sequential, Ascending, Multidose Study to Evaluate the Safety and Efficacy of Linaclotide in Pediatric Participants (Age 2 to 5 Years) With Functional Constipation

Study identification

NCT ID
NCT04110145
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Allergan
Industry
Enrollment
35 participants

Conditions and interventions

Interventions

  • Linaclotide Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
2 Years to 5 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 13, 2019
Primary completion
Apr 19, 2021
Completion
Apr 19, 2021
Last update posted
Apr 25, 2022

2019 – 2021

United States locations

U.S. sites
18
U.S. states
12
U.S. cities
18
Facility City State ZIP Site status
Central Research Associates, Inc Birmingham Alabama 35205
HealthStar Research Hot Springs Arkansas 71913
Preferred Clinical Research Partners Little Rock Arkansas 72211
Advanced Research Center Anaheim California 92805
Kindred Medical Institute for Clinical Trials, LLC Corona California 92879
Center for Clinical Trials, LLC Paramount California 90723
Prohealth Research Center Doral Florida 33166
South Miami Medical & Research Group, Inc. Miami Florida 33155
River Birch Research Alliance, LLC Blue Ridge Georgia 30513
SleepCare Research Institute, Inc. Stockbridge Georgia 30281
Virgo Carter Pediatrics Silver Spring Maryland 20910
Minnesota Gastroenterology PA Minneapolis Minnesota 55413
David M. Headley, MD, P.A. Port Gibson Mississippi 39150
Foundation Pediatrics Med Clinical Research Partners, LLC East Orange New Jersey 07108
Advantage Clinical Trials The Bronx New York 10468
Coastal Pediatric Research Charleston South Carolina 29414
Coastal Pediatric Research Mt. Pleasant South Carolina 29464
Clinical Research Partners, LLC Richmond Virginia 23220

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04110145, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 25, 2022 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04110145 live on ClinicalTrials.gov.

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