Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Psoriatic Arthritis Who Are Naive to Biologic DMARD Therapy
Public ClinicalTrials.gov record NCT04115748. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-blind, Placebo and Adalimumab-controlled Study to Evaluate the Efficacy and Safety of Filgotinib in Subjects With Active Psoriatic Arthritis Who Are Naive to Biologic DMARD Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to evaluate the effect of filgotinib compared to placebo as assessed by the American College of Rheumatology 20% improvement (ACR20) response in participants with active psoriatic arthritis who are naive to biologic disease-modifying anti-rheumatic drug (DMARD) therapy. The study consists of two parts, the Main Study and the Long Term Extension (LTE).
Study identification
- NCT ID
- NCT04115748
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 67 participants
Conditions and interventions
Conditions
Interventions
- Filgotinib Drug
- Adalimumab Drug
- Placebo to match filgotinib Drug
- Placebo to match adalimumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2, 2019
- Primary completion
- Jan 18, 2021
- Completion
- May 10, 2021
- Last update posted
- May 15, 2022
2019 – 2021
United States locations
- U.S. sites
- 24
- U.S. states
- 15
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Medvin Clinical Research | Covina | California | 91723 | — |
| Bay Area Arthritis and Osteoporosis | Brandon | Florida | 33511 | — |
| Omega Research Debary, LLC | DeBary | Florida | 32713 | — |
| San Marcus Research Clinic, Inc. | Miami | Florida | 33015 | — |
| Hmd Research Llc | Orlando | Florida | 32819 | — |
| Arthritis Center, Inc. | Palm Harbor | Florida | 85234 | — |
| ForCare Clinical Research | Tampa | Florida | 33613 | — |
| BayCare Medical Group, Inc. | Tampa | Florida | 33614 | — |
| North Georgia Rheumatology Group | Lawrenceville | Georgia | 30046 | — |
| Klein & Associates, M.D., P.A. | Hagerstown | Maryland | 21740 | — |
| Clinical Research Institute of Michigan, LLC | Saint Clair Shores | Michigan | 48081 | — |
| St. Paul Rheumatology, P.A. | Eagan | Minnesota | 55121 | — |
| Arthritis Consultants, Inc. | St Louis | Missouri | 63141 | — |
| Physician Research Collaaboration, LLCs | Lincoln | Nebraska | 68516 | — |
| Atlantic Coast Research | Toms River | New Jersey | 08755 | — |
| Joint and Muscle Research Institute | Charlotte | North Carolina | 28204 | — |
| Paramount Medical Research & Consulting, LLC | Middleburg Heights | Ohio | 44130 | — |
| Clinical Research Source Inc | Perrysburg | Ohio | 43551 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Articularis Healthcare Inc, dba, Columbia Arthritis Center, PA | Columbia | South Carolina | 29204 | — |
| ACME Research, LLC | Orangeburg | South Carolina | 29118 | — |
| Arthritis & Osteoporosis Clinic of Brazos Valley (Drug Shipment Address) | College Station | Texas | 77845 | — |
| Southwest Rheumatology Research, LLC | Mesquite | Texas | 75150 | — |
| West Virginia Research Institute PLLC | South Charleston | West Virginia | 25309 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 50 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04115748, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 15, 2022 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04115748 live on ClinicalTrials.gov.