Phase 2B Study to Evaluate the Efficacy of Bentracimab (PB2452) in Reversal of Ticagrelor in Subjects Aged 50-80 Years Old
Public ClinicalTrials.gov record NCT04122170. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2B, Randomized, Double-blind, Multicenter, Placebo-controlled Study to Evaluate the Efficacy of Bentracimab (PB2452) in Reversing Ticagrelor in Subjects Aged 50 to 80 Years Old
Study identification
- NCT ID
- NCT04122170
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- SFJ Pharmaceuticals, Inc.
- Industry
- Enrollment
- 207 participants
Conditions and interventions
Conditions
Interventions
- Ticagrelor Oral Tablet - Pre-Treatment Drug
- Aspirin (ASA) Oral Tablet - Pre-Treatment Drug
- Bentracimab (PB2452) Infusion Drug
- Placebo (0.9% Sodium chloride) infusion Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 23, 2019
- Primary completion
- Aug 31, 2021
- Completion
- Aug 31, 2021
- Last update posted
- Apr 7, 2024
2019 – 2021
United States locations
- U.S. sites
- 13
- U.S. states
- 9
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Woodland Research Northwest, LLC | Rogers | Arkansas | 72758 | — |
| WCCT Global, Inc. | Cypress | California | 90630 | — |
| Pacific Research Network | San Diego | California | 92103 | — |
| Clinical Pharmacology of Miami, LLC | Miami | Florida | 33014-3616 | — |
| PPD Development, LP | Orlando | Florida | 32806 | — |
| Altasciences Clinical Kansas, Inc. | Overland Park | Kansas | 66212 | — |
| BioPharma Services USA Inc. (BPSUSA) | St Louis | Missouri | 63141 | — |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | — |
| Aventiv Research Inc. | Columbus | Ohio | 43213 | — |
| Remington-Davis, Inc. | Columbus | Ohio | 43215 | — |
| VitaLink Research - Greenville | Greenville | South Carolina | 29615 | — |
| VitaLink Research - Spartanburg | Spartanburg | South Carolina | 29303 | — |
| Rebecca Wood-Horrall | Austin | Texas | 78744 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04122170, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 7, 2024 · Synced Jul 24, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04122170 live on ClinicalTrials.gov.