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Not listed Phase 1 Interventional

Study of AMV564 in Subjects With Advanced Solid Tumors

ClinicalTrials.gov ID: NCT04128423

Public ClinicalTrials.gov record NCT04128423. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 3:33 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Dose Escalation With Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMV564 Alone and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This Phase 1 study is designed to assess the safety, tolerability, pharmacokinetics, and preliminary efficacy of AMV564 alone and in combination with Pembrolizumab in patients with advanced solid tumors.

Study identification

NCT ID
NCT04128423
Recruitment status
Not listed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Amphivena Therapeutics, Inc.
Industry
Enrollment
65 participants

Conditions and interventions

Interventions

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 8, 2019
Primary completion
Dec 14, 2021
Completion
Dec 30, 2021
Last update posted
Oct 18, 2021

2019 – 2021

United States locations

U.S. sites
11
U.S. states
7
U.S. cities
11
Facility City State ZIP Site status
UCLA Los Angeles California 90095
Advent Health Orlando Florida 32803
Moffitt Cancer Center Tampa Florida 33612
Northwestern University Chicago Illinois 60611
Duke University Medical Center Durham North Carolina 27710
The Christ Hospital Cincinnati Ohio 45255
The Ohio State University Columbus Ohio 43202
MD Anderson Cancer Center Houston Texas 77030
NEXT Oncology San Antonio Texas 78229
University of Virginia Charlottesville Virginia 22908
Peninsula Cancer Institute Newport News Virginia 23601

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04128423, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 18, 2021 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04128423 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →