PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study
Public ClinicalTrials.gov record NCT04129931. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to evaluate several interventions given to participants with severe asthma. Interventions are administered in a crossover manner with 16-week treatment periods followed by 8 to 16 week washout.
Study identification
- NCT ID
- NCT04129931
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 950 participants
Conditions and interventions
Conditions
Interventions
- MCT Drug
- Clazakizumab Drug
- Broncho-Vaxom Drug
- Imatinib Mesylate Drug
- Cavosonstat Drug
- Placebo Other
Drug · Other
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 19, 2019 (Actual)
- Primary completion
- Feb 19, 2025 (Actual)
- Completion
- Mar 19, 2025 (Actual)
- Last update posted
- Apr 1, 2026
2019 – 2025
United States locations
- U.S. sites
- 29
- U.S. states
- 16
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Scottsdale | Scottsdale | Arizona | 85259 | — |
| University of Arizona Tucson | Tucson | Arizona | 85724 | — |
| University of California Davis | Sacramento | California | 95817 | — |
| University of California San Diego: Airway Research & Clinical Trials Center | San Diego | California | 92103 | — |
| University of California San Diego: La Jolla Altman Clinical Translation Research Institute | San Diego | California | 92121 | — |
| University of California San Francisco | San Francisco | California | 94143 | — |
| Children's Hospital Colorado | Aurora | Colorado | 80045 | — |
| University of Colorado Denver | Aurora | Colorado | 80045 | — |
| National Jewish Health | Denver | Colorado | 802006 | — |
| Yale University | New Haven | Connecticut | 06520 | — |
| University of South Florida | Tampa | Florida | 33613 | — |
| University of Illinois at Chicago | Chicago | Illinois | 60608 | — |
| Ann & Robert H. Lurie Children's Hospital | Chicago | Illinois | 60611 | — |
| Northwestern Universtiy | Chicago | Illinois | 60611 | — |
| Rush University | Chicago | Illinois | 60612 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Riley Hospital for Children | Indianapolis | Indiana | 46202 | — |
| University of Kansas | Kansas City | Kansas | 66160 | — |
| Boston Children's Hospital | Boston | Massachusetts | 02115 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| Mount Sinai | New York | New York | 10029 | — |
| Columbia University Medical Center | New York | New York | 10031 | — |
| Wake Forest University | Winston-Salem | North Carolina | 27104 | — |
| Cleveland Clinic | Cleveland | Ohio | 44106 | — |
| University Hospitals Rainbow Babies & Children's Hospital | Cleveland | Ohio | 44106 | — |
| Vanderbilt University | Nashville | Tennessee | 37232 | — |
| University of Wisconsin-Madison | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04129931, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 1, 2026 · Synced Oct 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04129931 live on ClinicalTrials.gov.