Study to Evaluate the Efficacy and Safety of Tilpisertib in Adults With Moderately to Severely Active Ulcerative Colitis
Public ClinicalTrials.gov record NCT04130919. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Blinded, Randomized, Placebo-Controlled Study Evaluating the Efficacy and Safety of GS-4875 in Subjects With Moderately to Severely Active Ulcerative Colitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to demonstrate the efficacy of tilpisertib (formerly GS-4875) compared with placebo control in achieving clinical remission per modified Mayo Clinic Score (MCS) in adults with moderately to severely active ulcerative colitis (UC).
Study identification
- NCT ID
- NCT04130919
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 19 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 20, 2019 (Actual)
- Primary completion
- Feb 25, 2021 (Actual)
- Completion
- Dec 14, 2021 (Actual)
- Last update posted
- Aug 24, 2022
2019 – 2021
United States locations
- U.S. sites
- 23
- U.S. states
- 12
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Gut P.C., dba Digestive Health Specialists of the Southeast | Dothan | Alabama | 36305 | — |
| Om Research LLC | Lancaster | California | 93534 | — |
| United Medical Doctors | Murrieta | California | 92563 | — |
| Alliance Clinical Research | Poway | California | 92064 | — |
| Alliance Medical Research | Coral Springs | Florida | 33071 | — |
| Encore Borland-Groover Clinical Research | Jacksonville | Florida | 32256 | — |
| A Plus Research, Inc | Miami | Florida | 33144 | — |
| BRCR Medical Center Inc. | Plantation | Florida | 33322 | — |
| Advanced Medical Research Center | Port Orange | Florida | 32127 | — |
| Gastrointestinal Specialists of Georgia | Marietta | Georgia | 30060 | — |
| Atlanta Gastroenterology Specialists, PC | Suwanee | Georgia | 30024 | — |
| Louisiana Research Center, LLC | Shreveport | Louisiana | 71105 | — |
| Kansas City Research Institute | Kansas City | Missouri | 64131 | — |
| Advanced Biomedical Research of America | Las Vegas | Nevada | 89123 | — |
| Consultants for Clinical Research | Cincinnati | Ohio | 45219 | — |
| Gastroenterology Associates of Orangeburg | Orangeburg | South Carolina | 29118 | — |
| Vanderbilt University Medical Center - IBD Clinic | Nashville | Tennessee | 37212-1375 | — |
| Allied Digestive Disease Center | Cypress | Texas | 77429 | — |
| Southwest Clinical Trials | Houston | Texas | 77074 | — |
| Clinical Associates in Research Therapeutics of America, LLC | San Antonio | Texas | 78212 | — |
| Texas Digestive Disease Consultants | San Marcos | Texas | 78666 | — |
| Texas Digestive Disease Consultants | Southlake | Texas | 76092 | — |
| Allegiance Research Specialists, LLC | Wauwatosa | Wisconsin | 53225 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 26 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04130919, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 24, 2022 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04130919 live on ClinicalTrials.gov.