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Completed No phase listed Observational Accepts healthy volunteers

Precision Crohn's Disease Management Utilizing Predictive Protein Panels (ENvISION)

ClinicalTrials.gov ID: NCT04131504

Public ClinicalTrials.gov record NCT04131504. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 10:13 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-Center, Prospective Study to Discover a Companion Diagnostic for Biologics Targeting TNF

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Crohn's disease and ulcerative colitis affect about 1.6 to 3 million people in the United States with many of those being young children and adolescents. Physicians need better ways to inform decisions on therapy selection and recognize ongoing intestinal injury while on treatment. The main reason for this research study is to see if a blood test or stool test, which measures specific proteins, taken just before starting a new treatment for Crohn's disease can predict a patient's ability to achieve complete intestinal healing. The investigators also want to see if the intensity of gut inflammation can be detected by measuring a separate set of proteins in the blood.

Study identification

NCT ID
NCT04131504
Recruitment status
Completed
Study type
Observational
Phase
Not listed
Enrollment
239 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
1 Year to 22 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 15, 2019
Primary completion
Oct 30, 2023
Completion
Oct 30, 2023
Last update posted
Jan 29, 2024

2019 – 2023

United States locations

U.S. sites
4
U.S. states
3
U.S. cities
4
Facility City State ZIP Site status
Connecticut Children's Medical Center Hartford Connecticut 06016
Cincinnati Children's Hospital Cincinnati Ohio 45229
Nationwide Children's Hospital Columbus Ohio 43205
Medical College of Wisconsin Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04131504, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 29, 2024 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04131504 live on ClinicalTrials.gov.

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