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Completed Phase 2Phase 3 Interventional Results available

Dose Ranging Study to Assess the Efficacy and Safety of Voclosporin Ophthalmic Solution in Subjects With Dry Eye Syndrome

ClinicalTrials.gov ID: NCT04147650

Public ClinicalTrials.gov record NCT04147650. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 26, 2026, 1:29 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Masked, Vehicle-Controlled, Dose Ranging Study to Assess the Efficacy and Safety of Voclosporin Ophthalmic Solution (VOS) in Subjects With Dry Eye Syndrome (DES)

Study identification

NCT ID
NCT04147650
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Aurinia Pharmaceuticals Inc.
Industry
Enrollment
508 participants

Conditions and interventions

Interventions

  • 0.05% Voclosporin Ophthalmic Solution (VOS) Drug
  • 0.10% VOS Drug
  • 0.20% VOS Drug
  • Vehicle Ophthalmic Solution Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 13, 2019
Primary completion
Sep 16, 2020
Completion
Oct 7, 2020
Last update posted
Dec 9, 2021

2019 – 2020

United States locations

U.S. sites
9
U.S. states
7
U.S. cities
9
Facility City State ZIP Site status
Aurinia Investigative Center Newport Beach California 92663
Aurinia Investigative Center Colorado Springs Colorado 80907
Aurinia Investigative Center Louisville Kentucky 40206
Aurinia Investigative Center Lewiston Maine 04240
Aurinia Investigative Center Andover Massachusetts 01810
Aurinia Investigative Center Raynham Massachusetts 02767
Aurinia Investigative Center Cranberry Township Pennsylvania 16066
Aurinia Investigative Center Memphis Tennessee 38119
Aurinia Investigative Center Nashville Tennessee 37205

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04147650, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 9, 2021 · Synced Jun 26, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04147650 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →