A Clinical Study of NLY01 in Patient's With Early Parkinson's Disease
Public ClinicalTrials.gov record NCT04154072. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of 36 Weeks of Treatment With NLY01 in Early-stage Parkinson's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a phase 2 study designed to assess the safety, tolerability and efficacy of NLY01 in subjects with early untreated Parkinson's disease (PD). Evidence suggests NLY01, a pegylated form of exenatide, may be beneficial in PD and is being developed as a potential treatment for neurodegenerative disorders.
Study identification
- NCT ID
- NCT04154072
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 255 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 30 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 27, 2020 (Actual)
- Primary completion
- Feb 14, 2023 (Actual)
- Completion
- Feb 14, 2023 (Actual)
- Last update posted
- Sep 19, 2024
2020 – 2023
United States locations
- U.S. sites
- 60
- U.S. states
- 27
- U.S. cities
- 52
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| St. Joseph's Hospital and Medical Center - Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Movement Disorders Center | Scottsdale | Arizona | 85258 | — |
| Mayo Clinic Arizona, Mayo Clinic Scottsdale | Scottsdale | Arizona | 85259 | — |
| Banner Sun Health Research Institute | Sun City | Arizona | 85351 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| University of California, Irvine | Irvine | California | 92697 | — |
| Keck School of Medicine of USC/University of Southern California | Los Angeles | California | 90033 | — |
| University of California, Los Angeles, Center for Neurotherapeutics | Los Angeles | California | 90095 | — |
| SC3 Research | Pasadena | California | 91105 | — |
| University of California Davis Health | Sacramento | California | 95816 | — |
| University of California, San Francisco | San Francisco | California | 94143 | — |
| University of Colorado | Denver | Colorado | 80204 | — |
| Rocky Mountain Movement Disorder Center | Englewood | Colorado | 80113 | — |
| Institute for Neurodegenerative Disorders | New Haven | Connecticut | 06510 | — |
| Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| Parkinson's Disease and Movement Disorder Center | Boca Raton | Florida | 33486 | — |
| Nova Clinical Research | Bradenton | Florida | 34209 | — |
| University of Florida | Gainesville | Florida | 32608 | — |
| Infinity Clinical Research | Hollywood | Florida | 33024 | — |
| Mayo Clinic Florida | Jacksonville | Florida | 32224 | — |
| Visionary Investigators Network | Miami | Florida | 33133 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| University of South Florida | Tampa | Florida | 33613 | — |
| Charter Research | Winter Park | Florida | 32159 | — |
| Augusta University | Augusta | Georgia | 30912 | — |
| NeuroStudies | Decatur | Georgia | 30033 | — |
| Northwestern Medical Group Neurology Clinic | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| SIU Medicine | Springfield | Illinois | 62702 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Maryland, Neurology Ambulatory Center, Maryland Parkinson's Disease and Movement Disorder Center | Baltimore | Maryland | 21201 | — |
| Johns Hopkins University School of Medicine | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital Clinical Trials Pharmacy | Boston | Massachusetts | 02114 | — |
| Boston University Medical Center | Boston | Massachusetts | 02118 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| University of Michigan Hospital | Ann Arbor | Michigan | 48109 | — |
| Quest Research Institute | Farmington Hills | Michigan | 48334 | — |
| Henry Ford West Bloomfield Hospital | West Bloomfield | Michigan | 48322 | — |
| Struthers Parkinson's Center | Golden Valley | Minnesota | 55427 | — |
| University of Minnesota Delaware Clinical Research Unit | Minneapolis | Minnesota | 55414 | — |
| Neurology Specialists of Monmouth County | West Long Branch | New Jersey | 07764 | — |
| NYU Langone Medical Center, The Marlene and Paolo Fresco Institute for Parkinson's and Movement Disorders | New York | New York | 10017 | — |
| Neurological Institute, Columbia University Medical Center | New York | New York | 10032 | — |
| UNC CTRC | Chapel Hill | North Carolina | 27599 | — |
| Duke University Medical Center | Durham | North Carolina | 27705 | — |
| Raleigh Neurology | Raleigh | North Carolina | 27607 | — |
| Wake Forest Baptist Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| The Ohio State University Wexner Medical Center | Columbus | Ohio | 43210 | — |
| University of Toledo, Gardner-McMaster Parkinson Center | Toledo | Ohio | 43614 | — |
| The Movement Disorder Clinic of Oklahoma | Tulsa | Oklahoma | 74136 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19107 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| Booth Gardner Parkinson's Care Center | Kirkland | Washington | 98034 | — |
| Froedtert Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04154072, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 19, 2024 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04154072 live on ClinicalTrials.gov.