A Study to Evaluate LTI-01 in Patients With Infected, Non-draining Pleural Effusions
Public ClinicalTrials.gov record NCT04159831. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Placebo-controlled, Double-blind, Dose-ranging Study Evaluating LTI-01 (Single-chain Urokinase Plasminogen Activator, scuPA) in Patients With Infected, Non-draining Pleural Effusions
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The LTI-01-2001 study is a double-blind, placebo-controlled, Phase 2 study to evaluate LTI-01 (single-chain urokinase plasminogen activator, scuPA) in patients with infected, non-draining pleural effusions.
Study identification
- NCT ID
- NCT04159831
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 44 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 26, 2020 (Actual)
- Primary completion
- Mar 31, 2022 (Actual)
- Completion
- Jul 28, 2022 (Actual)
- Last update posted
- Mar 30, 2023
2020 – 2022
United States locations
- U.S. sites
- 33
- U.S. states
- 22
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| UC San Diego Health Jacobs Medical Center | La Jolla | California | 92037 | — |
| University of California (UCLA) | Los Angeles | California | 90095 | — |
| UC Davis Medical Group | Sacramento | California | 95816 | — |
| University of Colorado | Aurora | Colorado | 80445 | — |
| Yale School of Medicine | New Haven | Connecticut | 06519 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| The University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Maryland School of Medicine | Baltimore | Maryland | 21201 | — |
| Johns Hopkins University | Baltimore | Maryland | 21205 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Lahey Hospital and Medical Center | Burlington | Massachusetts | 01805 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| St. Luke's Health System | Kansas City | Missouri | 64111 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| CHI CUMC Bergan Mercy | Omaha | Nebraska | 68124 | — |
| North Shore - Long Island Jewish Medical Center | Queens | New York | 11040 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Duke University | Durham | North Carolina | 27705 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| The Pennsylvania State University | Hershey | Pennsylvania | 17033 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Temple University | Philadelphia | Pennsylvania | 19140 | — |
| Vanderbilt Medical Center | Nashville | Tennessee | 37232 | — |
| The University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| The University of Texas Health Science Center | Houston | Texas | 77030 | — |
| University of Utah | Salt Lake City | Utah | 84112 | — |
| INOVA | Fairfax | Virginia | 22031 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23219 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04159831, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 30, 2023 · Synced Oct 29, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04159831 live on ClinicalTrials.gov.