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Completed Phase 2 Interventional Results available

A Study to Evaluate the Safety and Efficacy of VIB4920 in Participants With Rheumatoid Arthritis

ClinicalTrials.gov ID: NCT04163991

Public ClinicalTrials.gov record NCT04163991. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 3:17 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Mechanistic Insight and Dosage Optimization Study of the Efficacy and Safety of VIB4920 in Patients With Rheumatoid Arthritis (RA)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of the study is to evaluate the efficacy, safety, and pharmacokinetics (PK) of VIB4920 (formerly MEDI4920) in adult participants with rheumatoid arthritis (RA).

Study identification

NCT ID
NCT04163991
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Amgen
Industry
Enrollment
78 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 99 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 9, 2019 (Actual)
Primary completion
Dec 28, 2021 (Actual)
Completion
Dec 28, 2021 (Actual)
Last update posted
Dec 17, 2024

2019 – 2021

United States locations

U.S. sites
18
U.S. states
12
U.S. cities
18
Facility City State ZIP Site status
Research Site Anniston Alabama 36207 —
Research Site Sun City Arizona 85704 —
Research Site Upland California 91786 —
Research Site Clearwater Florida 33765 —
Research Site Margate Florida 33063 —
Research Site Miami Lakes Florida 33014 —
Research Site Zephyrhills Florida 33542 —
Research Site Atlanta Georgia 30342 —
Research Site Lexington Kentucky 40504 —
Research Site Wheaton Maryland 20902 —
Research Site Charlotte North Carolina 28210 —
Research Site Rocky Mount North Carolina 27804 —
Research Site Salisbury North Carolina 28144 —
Research Site Vandalia Ohio 45377 —
Research Site Norman Oklahoma 73069 —
Research Site Duncansville Pennsylvania 16635 —
Research Site Baytown Texas 77477 —
Research Site Dallas Texas 75231 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04163991, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 17, 2024 · Synced Oct 19, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04163991 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →