ClinicalTrials.gov record
Efficacy and Safety of Vonoprazan Compared to Lansoprazole in Participants With Helicobacter Pylori Infection
ClinicalTrials.gov ID: NCT04167670
Public ClinicalTrials.gov record NCT04167670. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized Multicenter Study to Evaluate the Efficacy and Safety of Open-Label Dual Therapy With Oral Vonoprazan 20 mg or Double-Blind Triple Therapy With Oral Vonoprazan 20 mg Compared to Double-Blind Triple Therapy With Oral Lansoprazole 30 mg Daily in Patients With Helicobacter Pylori Infection
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To compare the efficacy of Helicobacter pylori (HP) eradication with vonoprazan dual and triple therapy regimens versus lansoprazole triple therapy regimen in participants with HP infection, excluding participants who had a clarithromycin or amoxicillin resistant strain of HP at baseline.
Study identification
- NCT ID
- NCT04167670
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,046 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 10, 2019 (Actual)
- Primary completion
- Mar 10, 2021 (Actual)
- Completion
- Mar 18, 2021 (Actual)
- Last update posted
- Apr 5, 2022
2019 – 2021
United States locations
- U.S. sites
- 106
- U.S. states
- 28
- U.S. cities
- 87
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group | Anniston | Alabama | 36207 | — |
| North Alabama Research Center, LLC | Athens | Alabama | 35611 | — |
| Synexus Clinical Research US, Inc. - Alabama | Birmingham | Alabama | 35211 | — |
| Medical Affiliated Research Center Inc | Huntsville | Alabama | 35801 | — |
| Synexus Clinical Research US, Inc. - East Valley Family Physicians, PLC | Chandler | Arizona | 85224 | — |
| Synexus Clinical Research US, Inc. - Central Arizona Medical Associates, PC | Mesa | Arizona | 85206 | — |
| Synexus Clinical Research US, Inc. - Desert Clinical Research, LLC | Mesa | Arizona | 85213 | — |
| Elite Clinical Studies - Phoenix - BTC - PPDS | Phoenix | Arizona | 85018 | — |
| Hope Research Institute LLC | Phoenix | Arizona | 85018 | — |
| Del Sol Research Management - BTC - PPDS | Tucson | Arizona | 85712 | — |
| Preferred Research Partners - ClinEdge - PPDS | Little Rock | Arkansas | 72211 | — |
| Applied Research Center of Little Rock | Little Rock | Arkansas | 72212 | — |
| Arkansas Gastroenterology | North Little Rock | Arkansas | 72117 | — |
| Atria Clinical Research - BTC - PPDS | North Little Rock | Arkansas | 72117 | — |
| Anaheim Clinical Trials LLC | Anaheim | California | 92801 | — |
| GW Research, Inc. - ClinEdge - PPDS | Chula Vista | California | 91910 | — |
| eStudySite - Chula Vista - PPDS | Chula Vista | California | 91911 | — |
| Kindred Medical Institute for Clinical Trials, LLC | Corona | California | 92879 | — |
| HB Clinical Trials, Inc. | Fountain Valley | California | 92708-7510 | — |
| OM Research LLC - Lancaster - ClinEdge - PPDS | Lancaster | California | 93534 | — |
| Torrance Clinical Research Institute | Lomita | California | 90717 | — |
| Southern California Research Institute Medical Group, Inc. | Los Angeles | California | 90045 | — |
| Facey Medical Foundation | Mission Hills | California | 91345 | — |
| Palmtree Clinical Research | Palm Springs | California | 92262 | — |
| Precision Research Institute | San Diego | California | 92114 | — |
| Medical Associates Research Group, Inc. | San Diego | California | 92123 | — |
| Paragon Rx Clinical, Inc. | Santa Ana | California | 92703 | — |
| Synexus Clinical Research US, Inc. | Colorado Springs | Colorado | 80909 | — |
| Western States Clinical Research, Inc. | Wheat Ridge | Colorado | 80033 | — |
| Gastroenterology Associates of Fairfield County | Bridgeport | Connecticut | 06606 | — |
| Connecticut Clinical Research Foundation | Bristol | Connecticut | 06010 | — |
| Riverside Clinical Research | Edgewater | Florida | 32132 | — |
| Research Centers of America - ERG | Hollywood | Florida | 33024 | — |
| Nature Coast Clinical Research | Inverness | Florida | 34452 | — |
| ENCORE Borland-Groover Clinical Research - ERN - PPDS | Jacksonville | Florida | 32256 | — |
| Columbus Clinical Services LLC | Miami | Florida | 33125 | — |
| Jesscan Medical Research | Miami | Florida | 33134 | — |
| Nuren Medical and Research Center | Miami | Florida | 33144 | — |
| Premier Research Associate-Miami | Miami | Florida | 33165 | — |
| G. Medical Center | Orlando | Florida | 32807 | — |
| Advanced Gastroenterology Associates, LLC | Palm Harbor | Florida | 34684 | — |
| Innovation Medical Research Center | Palmetto Bay | Florida | 33157 | — |
| Synexus Clinical Research US, Inc. - St. Petersburg | Pinellas Park | Florida | 33781 | — |
| Precision Clinical Research, LLC | Sunrise | Florida | 33351 | — |
| Guardian Angel Research Center | Tampa | Florida | 33614 | — |
| Atlanta Gastroenterology Associates | Atlanta | Georgia | 30342 | — |
| Nexgen Research Center | Atlanta | Georgia | 30345 | — |
| Gastroenterology Associates of Central Georgia, LLC | Macon | Georgia | 31201 | — |
| In Quest Medical Research - ClinEdge - PPDS | Peachtree Corners | Georgia | 30071 | — |
| IL Gastroenterology Group | Gurnee | Illinois | 60031 | — |
| Summit Digestive & Liver Disease Specialists | Oakbrook Terrace | Illinois | 60181 | — |
| Gastroenterology Health Partners, PLLC | New Albany | Indiana | 47150 | — |
| Iowa Digestive Disease Center | Clive | Iowa | 50325 | — |
| Clinical Trials Management LLC | Covington | Louisiana | 70433 | — |
| CroNOLA, LLC. | Houma | Louisiana | 70360 | — |
| Clinical Trials Management LLC | Metairie | Louisiana | 70006 | — |
| Meridian Clinical Research-(Rockville Maryland) | Rockville | Maryland | 20854 | — |
| Clinical Associates | Towson | Maryland | 21286 | — |
| Oakland Medical Research Center | Troy | Michigan | 48085 | — |
| The Alliance for Multispecialty Research, LLC | Kansas City | Missouri | 64114 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Heartland Clinical Research, Inc | Omaha | Nebraska | 68134 | — |
| Synexus Clinical Research US, Inc. - Site 1 | Henderson | Nevada | 89052 | — |
| Synexus Clinical Research US, Inc. - Site 2 | Henderson | Nevada | 89052 | — |
| Sierra Clinical Research - ClinEdge - PPDS | Las Vegas | Nevada | 89106 | — |
| Office - Site 1 | Las Vegas | Nevada | 89119 | — |
| Office - Site 2 | Las Vegas | Nevada | 89128 | — |
| Advanced Research Institute | Reno | Nevada | 89511 | — |
| Drug Trials America - ClinEdge | Hartsdale | New York | 10530 | — |
| Carolinas Research Center | Charlotte | North Carolina | 28215 | — |
| Duke University Medical Center | Durham | North Carolina | 27710-4000 | — |
| Medication Management LLC | Greensboro | North Carolina | 27408 | — |
| Carolina Research | Greenville | North Carolina | 27834 | — |
| Peters Medical Research, LLC - ClinEdge - PPDS | High Point | North Carolina | 27262 | — |
| Dayton Gastroenterology, Inc | Dayton | Ohio | 45415 | — |
| Prestige Clinical Research | Franklin | Ohio | 45005 | — |
| Central Sooner Research | Norman | Oklahoma | 73071 | — |
| Synexus Clinical Research US, Inc. - Anderson | Anderson | South Carolina | 29621 | — |
| Clinical Trials of South Carolina | Charleston | South Carolina | 29406 | — |
| Coastal Carolina Research Center | Mt. Pleasant | South Carolina | 29464 | — |
| Rapid City Medical Center LLP | Rapid City | South Dakota | 57701 | — |
| Multi Specialty Clinical Research | Johnson City | Tennessee | 37601 | — |
| Clinical Research Associates Inc | Nashville | Tennessee | 37203 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37212 | — |
| Inquest Clinical Research | Baytown | Texas | 77521 | — |
| Synexus Clinical Research US, Inc. - Dallas | Dallas | Texas | 75234 | — |
| Texas Tech University Health Sciences Center El Paso | El Paso | Texas | 79905 | — |
| Ben Taub General Hospital | Houston | Texas | 77030 | — |
| Precision Research Institute, LLC | Houston | Texas | 77036 | — |
| Biopharma Informatic, LLC | Houston | Texas | 77084 | — |
| Rio Grande Gastroenterology | McAllen | Texas | 78503 | — |
| Digestive System Healthcare | Pasadena | Texas | 77505 | — |
| Pearland Physicians | Pearland | Texas | 77581 | — |
| Synexus Clinical Research US, Inc. - Plano | Plano | Texas | 75093 | — |
| Quality Research Inc | San Antonio | Texas | 78209 | — |
| Gastroenterology Research of San Antonio (GERSA) | San Antonio | Texas | 78229 | — |
| San Antonio Gastroenterology Associates Clinical Trials (SAGACT PLLC) | San Antonio | Texas | 78229 | — |
| Southern Star Research Institute, LLC | San Antonio | Texas | 78229 | — |
| Synexus Clinical Research US, Inc. - Layton | Layton | Utah | 84041 | — |
| Advanced Research Institute | Ogden | Utah | 84405 | — |
| University of Utah Hospital- Health Sciences Center - PPDS | Salt Lake City | Utah | 84132-0001 | — |
| New River Valley Research Institute | Christiansburg | Virginia | 24073 | — |
| Verity Research, Inc. | Fairfax | Virginia | 22031 | — |
| Blue Ridge Medical Research | Lynchburg | Virginia | 24502 | — |
| Washington Gastroenterology | Bellevue | Washington | 98004 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 47 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04167670, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 5, 2022 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04167670 live on ClinicalTrials.gov.