ClinicalTrials.gov record
Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer
ClinicalTrials.gov ID: NCT04172532
Public ClinicalTrials.gov record NCT04172532. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2 Study of M3814 (Peposertib) in Combination With Hypofractionated Radiotherapy for the Treatment of Locally Advanced Pancreatic Adenocarcinoma
Study identification
- NCT ID
- NCT04172532
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- National Cancer Institute (NCI)
- NIH
- Enrollment
- 92 participants
Conditions and interventions
Interventions
- Biopsy Procedure Procedure
- Biospecimen Collection Procedure
- Computed Tomography Procedure
- Hypofractionated Radiation Therapy Radiation
- Magnetic Resonance Imaging Procedure
- Peposertib Drug
- Placebo Administration Other
Procedure · Radiation · Drug + 1 more
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 10, 2021
- Primary completion
- Jul 31, 2026
- Completion
- Jul 31, 2026
- Last update posted
- May 19, 2026
2021 – 2026
United States locations
- U.S. sites
- 44
- U.S. states
- 17
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010 | Recruiting |
| UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care | Irvine | California | 92612 | Recruiting |
| City of Hope at Irvine Lennar | Irvine | California | 92618 | Suspended |
| UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange | California | 92868 | Recruiting |
| University of California Davis Comprehensive Cancer Center | Sacramento | California | 95817 | Recruiting |
| UCHealth University of Colorado Hospital | Aurora | Colorado | 80045 | Recruiting |
| Sibley Memorial Hospital | Washington D.C. | District of Columbia | 20016 | Recruiting |
| Northwestern University | Chicago | Illinois | 60611 | Active, not recruiting |
| University of Kansas Clinical Research Center | Fairway | Kansas | 66205 | Recruiting |
| HaysMed | Hays | Kansas | 67601 | Recruiting |
| University of Kansas Cancer Center | Kansas City | Kansas | 66160 | Recruiting |
| Lawrence Memorial Hospital | Lawrence | Kansas | 66044 | Recruiting |
| The University of Kansas Cancer Center - Olathe | Olathe | Kansas | 66061 | Recruiting |
| University of Kansas Cancer Center-Overland Park | Overland Park | Kansas | 66210 | Recruiting |
| Mercy Hospital Pittsburg | Pittsburg | Kansas | 66762 | Suspended |
| Salina Regional Health Center | Salina | Kansas | 67401 | Recruiting |
| University of Kansas Health System Saint Francis Campus | Topeka | Kansas | 66606 | Recruiting |
| University of Kansas Hospital-Westwood Cancer Center | Westwood | Kansas | 66205 | Recruiting |
| University of Kentucky/Markey Cancer Center | Lexington | Kentucky | 40536 | Withdrawn |
| Wayne State University/Karmanos Cancer Institute | Detroit | Michigan | 48201 | Active, not recruiting |
| Weisberg Cancer Treatment Center | Farmington Hills | Michigan | 48334 | Active, not recruiting |
| University Health Truman Medical Center | Kansas City | Missouri | 64108 | Recruiting |
| University of Kansas Cancer Center - North | Kansas City | Missouri | 64154 | Recruiting |
| University of Kansas Cancer Center - Lee's Summit | Lee's Summit | Missouri | 64064 | Recruiting |
| University of Kansas Cancer Center at North Kansas City Hospital | North Kansas City | Missouri | 64116 | Suspended |
| Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center | Lebanon | New Hampshire | 03756 | Active, not recruiting |
| Saint Barnabas Medical Center | Livingston | New Jersey | 07039 | Recruiting |
| Monmouth Medical Center | Long Branch | New Jersey | 07740 | Recruiting |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08903 | Recruiting |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | Active, not recruiting |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | 10016 | Active, not recruiting |
| Mount Sinai Hospital | New York | New York | 10029 | Recruiting |
| NYP/Weill Cornell Medical Center | New York | New York | 10065 | Recruiting |
| Montefiore Medical Center-Einstein Campus | The Bronx | New York | 10461 | Active, not recruiting |
| Montefiore Medical Center - Moses Campus | The Bronx | New York | 10467 | Active, not recruiting |
| Wake Forest University at Clemmons | Clemmons | North Carolina | 27012 | Active, not recruiting |
| Wake Forest Baptist Health - Wilkes Medical Center | Wilkesboro | North Carolina | 28659 | Active, not recruiting |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | Active, not recruiting |
| University of Pittsburgh Cancer Institute (UPCI) | Pittsburgh | Pennsylvania | 15232 | Recruiting |
| Vanderbilt University/Ingram Cancer Center | Nashville | Tennessee | 37232 | Suspended |
| Huntsman Cancer Institute/University of Utah | Salt Lake City | Utah | 84112 | Recruiting |
| VCU Massey Comprehensive Cancer Center | Richmond | Virginia | 23298 | Recruiting |
| University of Wisconsin Carbone Cancer Center - Eastpark Medical Center | Madison | Wisconsin | 53718 | Recruiting |
| University of Wisconsin Carbone Cancer Center - University Hospital | Madison | Wisconsin | 53792 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04172532, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 19, 2026 · Synced May 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04172532 live on ClinicalTrials.gov.