Dupilumab for the Treatment of Chronic Spontaneous Urticaria in Patients Who Remain Symptomatic Despite the Use of H1 Antihistamine and Who Are naïve to, Intolerant of, or Incomplete Responders to Omalizumab (LIBERTY-CSU CUPID)
Public ClinicalTrials.gov record NCT04180488. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Master Protocol of Three Randomized, Double-blind, Placebo Controlled, Multi-center, Parallel-group Studies of Dupilumab in Patients With Chronic Spontaneous Urticaria (CSU) Who Remain Symptomatic Despite the Use of H1 Antihistamine Treatment in Patients naïve to Omalizumab and in Patients Who Are Intolerant or Incomplete Responders to Omalizumab
Study identification
- NCT ID
- NCT04180488
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Sanofi
- Industry
- Enrollment
- 397 participants
Conditions and interventions
Conditions
Interventions
- Dupilumab SAR231893 Drug
- Placebo Drug
- non sedating H1-antihistamine Drug
Drug
Eligibility (public fields only)
- Age range
- 6 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 10, 2019
- Primary completion
- Jul 31, 2024
- Completion
- Oct 24, 2024
- Last update posted
- Aug 19, 2025
2019 – 2024
United States locations
- U.S. sites
- 16
- U.S. states
- 13
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| California Allergy and Asthma Medical Group, Inc. Site Number : 8400019 | Los Angeles | California | 90025 | — |
| Sarasota Clinical Research Site Number : 8400017 | Sarasota | Florida | 34239 | — |
| Lenus Research & Medical Group Site Number : 8400001 | Sweetwater | Florida | 33172 | — |
| University of South Florida Site Number : 8400006 | Tampa | Florida | 33613 | — |
| Aeroallergy Research Laboratories of Savannah, INC Site Number : 8400018 | Savannah | Georgia | 31406 | — |
| Allergy & Asthma Specialists, PSC Site Number : 8400020 | Owensboro | Kentucky | 42301 | — |
| Johns Hopkins University (Asthma and Allergy Center) Site Number : 8400016 | Baltimore | Maryland | 21224 | — |
| The Clinical Research Center, LLC Site Number : 8400009 | St Louis | Missouri | 63141 | — |
| UR Dermatology at College Town Site Number : 8400008 | Rochester | New York | 14642 | — |
| Immunocarolina LLC Site Number : 8400010 | Charlotte | North Carolina | 28277 | — |
| Bernstein Clinical Research Center Site Number : 8400014 | Cincinnati | Ohio | 45236 | — |
| Vital Prospects Clinical Research Institute, P.C. Site Number : 8400015 | Tulsa | Oklahoma | 74136 | — |
| Allergy and Clinical Immunology Associates Site Number : 8400024 | Pittsburgh | Pennsylvania | 15241 | — |
| National Allergy and ENT Site Number : 8400011 | Charleston | South Carolina | 29420 | — |
| Pharmaceutical Research & Consulting, Inc. Site Number : 8400003 | Dallas | Texas | 75231 | — |
| STAAMP Research, LLC Site Number : 8400007 | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 82 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04180488, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 19, 2025 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04180488 live on ClinicalTrials.gov.