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Terminated Phase 1 Interventional

An Open-label Study of ALPN-202 in Subjects With Advanced Malignancies

ClinicalTrials.gov ID: NCT04186637

Public ClinicalTrials.gov record NCT04186637. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 23, 2026, 12:34 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-label Study of ALPN-202 in Subjects With Advanced Malignancies (NEON-1)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a cohort-based, open-label dose escalation and expansion study in adults with advanced solid tumors or lymphoma, refractory or resistant to standard therapy, or without available standard or curative therapy.

Study identification

NCT ID
NCT04186637
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
Alpine Immune Sciences, Inc.
Industry
Enrollment
62 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 2, 2020 (Actual)
Primary completion
Nov 9, 2022 (Actual)
Completion
Feb 28, 2023 (Actual)
Last update posted
Jun 5, 2023

2020 – 2023

United States locations

U.S. sites
7
U.S. states
7
U.S. cities
7
Facility City State ZIP Site status
Investigational Site (004) Scottsdale Arizona 85258 —
Investigational Site (003) New Haven Connecticut 06520 —
Investigational Site (007) Lafayette Indiana 47905 —
Investigational Site (006) Louisville Kentucky 40202 —
Investigational Site (001) Grand Rapids Michigan 49546 —
Investigational Site (009) Portland Oregon 97213 —
Investigational Site (008) Pittsburgh Pennsylvania 15232 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04186637, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 5, 2023 · Synced Oct 23, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04186637 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →