Study to Evaluate Iovera®° in Adult Patients Undergoing Total Knee Arthroplasty
Public ClinicalTrials.gov record NCT04191031. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Double-blind, Randomized, Sham-controlled Study Assessing Opioid Utilization, Postoperative Pain and Function in Subjects Undergoing Total Knee Arthroplasty Treated With Presurgical Iovera®° or Sham Iovera®° Cryoneurolysis and Postsurgical Multimodal Pain Regimen
Study identification
- NCT ID
- NCT04191031
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Not applicable
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Enrollment
- 79 participants
Conditions and interventions
Conditions
Interventions
- ioveraº Device
- ioveraº sham Device
Device
Eligibility (public fields only)
- Age range
- 22 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 29, 2020
- Primary completion
- May 12, 2022
- Completion
- Jul 11, 2022
- Last update posted
- Jan 24, 2023
2020 – 2022
United States locations
- U.S. sites
- 7
- U.S. states
- 5
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Sah Orthopaedic Associates at the Institute for Joint Restoration | Fremont | California | 94538 | — |
| Lotus Clinical Research | Pasadena | California | 91105 | — |
| Phoenix Clinical Research | Tamarac | Florida | 33321 | — |
| Towson Orthopaedic Associates | Towson | Maryland | 21204 | — |
| Northwell Health | New York | New York | 10075 | — |
| First Surgical Hospital | Bellaire | Texas | 77401 | — |
| Legent Orthopedic Hospital | Carrollton | Texas | 75006 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04191031, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 24, 2023 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04191031 live on ClinicalTrials.gov.