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Completed Phase 2 Interventional Results available

Study of CVN424 in Parkinson's Disease Patients With Motor Fluctuations

ClinicalTrials.gov ID: NCT04191577

Public ClinicalTrials.gov record NCT04191577. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 25, 2026, 1:23 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of CVN424 in Parkinson's Disease Patients With Motor Fluctuations

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a phase 2 study, randomized, double-blind, placebo-controlled, multicenter study of oral CVN424 at two dose levels (low-dose and high-dose) in Parkinson's disease (PD) patients with motor fluctuations.

Study identification

NCT ID
NCT04191577
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Cerevance Beta, Inc.
Industry
Enrollment
136 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
30 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 1, 2019
Primary completion
Nov 5, 2021
Completion
Dec 12, 2021
Last update posted
Jul 2, 2024

2019 – 2021

United States locations

U.S. sites
21
U.S. states
13
U.S. cities
21
Facility City State ZIP Site status
Collaborative Neuroscience Network, LLC Long Beach California 90806 —
SC3 Research - Pasadena Pasadena California 91105 —
Parkinson's Disease and Movement Disorders Center of Boca Raton Boca Raton Florida 33486 —
Nova Clinical Research Bradenton Florida 34209 —
Premier Clinical Research Institute Miami Florida 33122 —
Parkinson's Disease Treatment Center of SW Florida Port Charlotte Florida 33980 —
Accel Research Site - Brain and Spine Institute of Port Orange Port Orange Florida 32127 —
USF Parkinson's Disease and Movement Disorders Center Tampa Florida 33613 —
Charter Research Winter Park Florida 32792 —
NeuroTrials Research, Inc. Atlanta Georgia 30328 —
Parkinson's Disease and Movement Disorder Center Kansas City Kansas 66160 —
Boston Clinical Trials Roslindale Massachusetts 02131 —
Quest Research Institute Farmington Hills Michigan 48334 —
Bio Behavioral Health Toms River New Jersey 08755 —
New York Neurology Associates New York New York 10003 —
M3 Wake Research Raleigh North Carolina 27612 —
Optimed Research Ltd Columbus Ohio 43235 —
Neurology Diagnostics Inc Dayton Ohio 45459 —
Prisma Health Greenville South Carolina 29615 —
Central Texas Neurology Consultants Round Rock Texas 78681 —
Inland Northwest Research, LLC Spokane Washington 99202 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04191577, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 2, 2024 · Synced Sep 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04191577 live on ClinicalTrials.gov.

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