Efficacy and Safety of Gefapixant (MK-7264) in Women With Chronic Cough and Stress Urinary Incontinence (MK-7264-042)
Public ClinicalTrials.gov record NCT04193176. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3b Randomized, Double-blind, Placebo Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Gefapixant in Women With Chronic Cough and Stress Urinary Incontinence
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of gefapixant, in improving symptoms of cough-induced stress urinary incontinence (SUI) in adult female participants with refractory or unexplained chronic cough. The primary hypothesis is that gefapixant is superior to placebo in reducing the frequency of cough-induced SUI episodes over 12 weeks.
Study identification
- NCT ID
- NCT04193176
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 376 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 10, 2020 (Actual)
- Primary completion
- Aug 18, 2022 (Actual)
- Completion
- Sep 2, 2022 (Actual)
- Last update posted
- Nov 5, 2024
2020 – 2022
United States locations
- U.S. sites
- 19
- U.S. states
- 13
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Center for Clinical Trials, LLC ( Site 0021) | Paramount | California | 90723 | — |
| Health Awareness, Inc. ( Site 0038) | Jupiter | Florida | 33458 | — |
| Well Pharma Medical Research, Corp. ( Site 0040) | Miami | Florida | 33173 | — |
| Lenus Research & Medical Group Llc ( Site 0007) | Sweetwater | Florida | 33172 | — |
| Florida Pulmonary Research Institute, LLC ( Site 0008) | Winter Park | Florida | 32789 | — |
| Paul A. Shapero, MD ( Site 0037) | Bangor | Maine | 04401 | — |
| Chesapeake Clinical Research, Inc ( Site 0022) | White Marsh | Maryland | 21162 | — |
| University of Missouri ENT & Allergy Center ( Site 0010) | Columbia | Missouri | 65201 | — |
| Alliance for Multispecialty Research, LLC ( Site 0035) | Las Vegas | Nevada | 89119 | — |
| Albuquerque Clinical Trials ( Site 0019) | Albuquerque | New Mexico | 87102 | — |
| American Health Research ( Site 0027) | Charlotte | North Carolina | 28277 | — |
| Clinical Research of Gastonia ( Site 0016) | Gastonia | North Carolina | 28054 | — |
| PMG Research of Wilmington ( Site 0004) | Wilmington | North Carolina | 28401 | — |
| Temple University ( Site 0003) | Philadelphia | Pennsylvania | 19140 | — |
| AAPRI Clinical Research Institute ( Site 0031) | Warwick | Rhode Island | 02886 | — |
| Diagnostics Research Group ( Site 0013) | San Antonio | Texas | 78229 | — |
| TPMG Clinical Research ( Site 0025) | Newport News | Virginia | 23606 | — |
| Tidewater Physician Multispecialty Group, PC ( Site 0028) | Williamsburg | Virginia | 23188 | — |
| Bellingham Asthma & Allergy ( Site 0006) | Bellingham | Washington | 98225 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 71 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04193176, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 5, 2024 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04193176 live on ClinicalTrials.gov.