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Completed Phase 1 Interventional

A Study to Evaluate the Safety of bb2121 in Subjects With High Risk, Newly Diagnosed Multiple Myeloma (NDMM)

ClinicalTrials.gov ID: NCT04196491

Public ClinicalTrials.gov record NCT04196491. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 6:43 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1, Open-label, Multicenter Study to Evaluate the Safety of bb2121 in Subjects With High Risk, Newly Diagnosed Multiple Myeloma (KarMMa-4)

Study identification

NCT ID
NCT04196491
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Celgene
Industry
Enrollment
13 participants

Conditions and interventions

Interventions

  • bb2121 Biological
  • Fludarabine Drug
  • Cyclophosphamide Drug
  • Lenalidomide Drug

Biological · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 26, 2020
Primary completion
Jun 6, 2023
Completion
Jun 6, 2023
Last update posted
Aug 22, 2023

2020 – 2023

United States locations

U.S. sites
22
U.S. states
15
U.S. cities
18
Facility City State ZIP Site status
Local Institution - 119 Phoenix Arizona 85054
Local Institution - 110 Los Angeles California 90095
Local Institution - 116 San Francisco California 94143
Local Institution - 106 Denver Colorado 80218
Local Institution - 101 Jacksonville Florida 32224
Local Institution - 113 Tampa Florida 33612
Local Institution - 108 Atlanta Georgia 30322
Local Institution - 123 Atlanta Georgia 30342
Local Institution - 115 Boston Massachusetts 02114
Local Institution - 122 Boston Massachusetts 02215
Local Institution - 117 Hackensack New Jersey 07601
Local Institution - 121 New York New York 10016
Local Institution - 109 New York New York 10029
Local Institution - 124 New York New York 10065
Local Institution - 120 Charlotte North Carolina 28207
Local Institution - 112 Portland Oregon 97239
Local Institution - 118 Philadelphia Pennsylvania 19104
Local Institution - 103 Nashville Tennessee 37203
Local Institution - 102 Dallas Texas 75390
Local Institution - 114 Houston Texas 77030
Local Institution - 104 Seattle Washington 98109-1024
Local Institution - 107 Milwaukee Wisconsin 53226-3522

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04196491, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 22, 2023 · Synced Jul 21, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04196491 live on ClinicalTrials.gov.

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