ClinicalTrials.gov record
The Cardiovascular Multi-dimensional Observational Investigation of the Use of PCSK9 Inhibitors (cvMOBIUS)
ClinicalTrials.gov ID: NCT04197453
Public ClinicalTrials.gov record NCT04197453. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 8, 2026, 8:10 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Study identification
- NCT ID
- NCT04197453
- Recruitment status
- Terminated
- Study type
- Observational
- Phase
- Not listed
- Lead sponsor
- Amgen
- Industry
- Enrollment
- 752 participants
Conditions and interventions
Conditions
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 40 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 5, 2019
- Primary completion
- Dec 20, 2020
- Completion
- Dec 20, 2020
- Last update posted
- Oct 14, 2021
2019 – 2020
United States locations
- U.S. sites
- 143
- U.S. states
- 35
- U.S. cities
- 129
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Mercy Gilbert Medical Center | Gilbert | Arizona | 85297 | — |
| Old Pueblo Cardiology | Tucson | Arizona | 85712 | — |
| Cardiovascular Research Foundation of Southern California | Beverly Hills | California | 90210 | — |
| Los Alamitos Cardiovascular | Los Alamitos | California | 90720 | — |
| Consortium of Attending Physicians for Research Investigations LLC | Los Angeles | California | 90448 | — |
| Nanavati Critical Care Cardiology Clinic | National City | California | 91950 | — |
| Rancho Cucamonga Clinical Trials | Rancho Cucamonga | California | 91730 | — |
| Eisenhower Desert Cardiology Center | Rancho Mirage | California | 92270 | — |
| San Diego Cardiac Center | San Diego | California | 92123 | — |
| Millennium Clinical Trials | Thousand Oaks | California | 91360 | — |
| Central Coast Cardiovascular | Ventura | California | 93003 | — |
| University of Colorado Memorial Health System | Colorado Springs | Colorado | 80909 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| Cardiology Associates of Fairfield County, PC | Stamford | Connecticut | 06905 | — |
| Bay Area Cardiology | Brandon | Florida | 33511 | — |
| Holy Cross Hospital Inc | Fort Lauderdale | Florida | 33308 | — |
| The Cardiac and Vascular Institute Research | Gainesville | Florida | 32605 | — |
| Baptist Heart Specialists | Jacksonville Beach | Florida | 32250 | — |
| Southwest Florida Research LLC | Naples | Florida | 34102 | — |
| Ocala Cardiovascular Research | Ocala | Florida | 34474 | — |
| Palm Harbor Medical Associates | Palm Harbor | Florida | 34684 | — |
| Cardiology Consultants | Pensacola | Florida | 32501 | — |
| Genesis Clinical Research Inc | Tampa | Florida | 33614 | — |
| Interventional Cardiac Consultants | Trinity | Florida | 34655 | — |
| Albany Internal Medicine | Albany | Georgia | 31707 | — |
| Piedmont Heart Institute | Atlanta | Georgia | 30309 | — |
| Accel Research Sites | Atlanta | Georgia | 30342 | — |
| First Georgia Physicians Group | Fayetteville | Georgia | 30214 | — |
| Northwest Heart Clinical Research LLC | Arlington Heights | Illinois | 60005 | — |
| John H Stroger Jr Hospital of Cook County | Chicago | Illinois | 60612 | — |
| Evanston Premier Healthcare Research LLC | Evanston | Illinois | 60201 | — |
| Advocate Lutheran General Hospital | Park Ridge | Illinois | 60068 | — |
| Prairie Cardiovascular Consultants | Springfield | Illinois | 62701 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| Saint Vincent Heart Center | Indianapolis | Indiana | 46290 | — |
| Reid Physician Associates | Richmond | Indiana | 47374 | — |
| Midwest Cardiovascular Research Foundation | Davenport | Iowa | 52803 | — |
| MercyOne Iowa Heart Center | West Des Moines | Iowa | 50266 | — |
| The University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Midwest Heart and Vascular Specialists | Overland Park | Kansas | 66211 | — |
| Premier Medical Group | Owensboro | Kentucky | 42303 | — |
| Grace Research LLC | Bossier City | Louisiana | 71111 | — |
| Heart Clinic of Hammond | Hammond | Louisiana | 70403 | — |
| Clinical Trials of America Inc | Monroe | Louisiana | 71201 | — |
| University Medical Center-New Orleans | New Orleans | Louisiana | 70112 | — |
| Ochsner Health Systems | New Orleans | Louisiana | 70121 | — |
| Willis Knighton Cardiology | Shreveport | Louisiana | 71103 | — |
| Grace Research LLC | Shreveport | Louisiana | 71105 | — |
| Louisiana Heart Center | Slidell | Louisiana | 70458 | — |
| MedStar Health Research Institute Chesapeake Cardiovascular Associates | Hyattsville | Maryland | 20782 | — |
| TidalHealth Peninsula Regional, Inc | Salisbury | Maryland | 21804 | — |
| McLaren Health | Bay City | Michigan | 48708 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Genesys Regional Medical Center | Grand Blanc | Michigan | 48439 | — |
| Michigan Heart | Ypsilanti | Michigan | 48197 | — |
| Minneapolis Heart Institute Foundation | Minneapolis | Minnesota | 55407 | — |
| Jackson Heart | Jackson | Mississippi | 39216 | — |
| Missouri Cardiovascular Specialists | Columbia | Missouri | 65201 | — |
| University of Missouri Health Care | Columbia | Missouri | 65212 | — |
| Cox Medical Centers | Springfield | Missouri | 65807 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| Saint Louis Heart and Vascular PC | St Louis | Missouri | 63136 | — |
| Methodist Physicians Clinic Heart Consultants | Omaha | Nebraska | 68114 | — |
| Palm Research Center Inc | Las Vegas | Nevada | 89128 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Advanced Heart Care LLC | Bridgewater | New Jersey | 08807 | — |
| Advanced Cardiology LLC | Cedar Knolls | New Jersey | 07927 | — |
| Overlook Hospital | Summit | New Jersey | 07901 | — |
| Virtua Health, Inc. | Voorhees Township | New Jersey | 08043 | — |
| Albany Medical College | Albany | New York | 12206 | — |
| Bassett Healthcare | Cooperstown | New York | 13326 | — |
| Long Island Cardiovascular Consultants | Lake Success | New York | 11042 | — |
| SJH Cardiology Associates | Liverpool | New York | 13088 | — |
| Winthrop University Hospital | Mineola | New York | 11501 | — |
| Northwell Health | New York | New York | 10011 | — |
| DiGiovanna Institute for Medical Education and Research | North Massapequa | New York | 11758 | — |
| Circuit Clinic | Orchard Park | New York | 14127 | — |
| Saratoga Clinical Research, LLC | Saratoga Springs | New York | 12866 | — |
| Stony Brook University Hospital | Stony Brook | New York | 11794 | — |
| Montefiore Medical Center - Bronx | The Bronx | New York | 10467 | — |
| Duke Heart Center Clinical Research | Durham | North Carolina | 27710 | — |
| Cone Health | Greensboro | North Carolina | 27401 | — |
| Medication Management, LLC | Greensboro | North Carolina | 27405 | — |
| Vidant Cardiology | Greenville | North Carolina | 27834 | — |
| Novant Health Heart and Vascular Institute | Monroe | North Carolina | 28112 | — |
| Coastal Carolina Health Care PA | New Bern | North Carolina | 28562 | — |
| Pinehurst Medical Clinic, Inc | Pinehurst | North Carolina | 28374 | — |
| WakeMed | Raleigh | North Carolina | 27610 | — |
| Sanford Cardiology | Sanford | North Carolina | 27330 | — |
| PMG Research of Piedmont HealthCare | Statesville | North Carolina | 28625 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| The Ohio State University, Wexner Medical Center | Columbus | Ohio | 43210 | — |
| Premier Cardiovascular | Dayton | Ohio | 45414 | — |
| Kettering Medical Center | Kettering | Ohio | 45429 | — |
| Heart House Research Foundation | Springfield | Ohio | 45504 | — |
| Saint Vincent Medical Center | Toledo | Ohio | 43608 | — |
| Central Oklahoma Early Detection Center | Edmond | Oklahoma | 73034 | — |
| Ascension St John Clinical Research Institute | Tulsa | Oklahoma | 74104 | — |
| Oklahoma State University Health Science Center | Tulsa | Oklahoma | 74127 | — |
| Lynn Institute of Tulsa | Tulsa | Oklahoma | 74135 | — |
| Central PA Physicians Group | Altoona | Pennsylvania | 16602 | — |
| Capital Area Research LLC | Camp Hill | Pennsylvania | 17011 | — |
| Chambersburg Hospital | Chambersburg | Pennsylvania | 17201 | — |
| Doylestown Health Cardiology | Doylestown | Pennsylvania | 18901 | — |
| The Heart Group of Lancaster General Health | Lancaster | Pennsylvania | 17603 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Kent Hospital | Warwick | Rhode Island | 02886 | — |
| AnMed Health | Anderson | South Carolina | 29621 | — |
| PMG Research of Charleston | Charleston | South Carolina | 29407 | — |
| Columbia Heart | Columbia | South Carolina | 29203 | — |
| Upstate Cardiology | Greenville | South Carolina | 29607 | — |
| Monument Health Clinical Research | Rapid City | South Dakota | 57701 | — |
| Diagnostic Cardiology Group | Chattanooga | Tennessee | 37404 | — |
| Stern Cardiovascular Foundation Inc | Germantown | Tennessee | 38138 | — |
| Parkway Cardiology Associates | Oak Ridge | Tennessee | 37830 | — |
| Seton Heart Institute | Austin | Texas | 78705 | — |
| Thyroid Endocrinology and Diabetes | Dallas | Texas | 75208 | — |
| Southwest Family Medicine Associates | Dallas | Texas | 75235 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Northwest Houston Cardiology | Houston | Texas | 77070 | — |
| North Dallas Research Associates | McKinney | Texas | 75069 | — |
| CardioVoyage | McKinney | Texas | 75071 | — |
| Texas Institute of Cardiology | McKinney | Texas | 75071 | — |
| Southern Endocrinology Associates PA | Mesquite | Texas | 75149 | — |
| Permian Research Foundation | Odessa | Texas | 79761 | — |
| Consano Clinical Research | San Antonio | Texas | 78258 | — |
| San Antonio Endovascular and Heart Institute | San Antonio | Texas | 78258 | — |
| Village Medical Centers | The Woodlands | Texas | 77382 | — |
| Northwest Houston Heart Center | Tomball | Texas | 77375 | — |
| Tyler Cardiovascular Consultants | Tyler | Texas | 75701 | — |
| Cardiology Consultants of Danville, Inc | Danville | Virginia | 24541 | — |
| Virginia Heart | Falls Church | Virginia | 22042 | — |
| Stroobants Cardiovascular Center | Lynchburg | Virginia | 24501 | — |
| Carient Heart and Vascular | Manassas | Virginia | 20109 | — |
| Cardiovascular Associates of Virginia | Midlothian | Virginia | 23114 | — |
| Tidewater Physicians Multispecialty Group Clinical Research | Newport News | Virginia | 23606 | — |
| York Clinical Research LLC | Norfolk | Virginia | 23510 | — |
| Multicare Institute for Research and Innovation | Puyallup | Washington | 98372 | — |
| Washington University | Seattle | Washington | 98014 | — |
| Marshall Cardiology | Huntington | West Virginia | 25701 | — |
| West Virginia University | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04197453, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 14, 2021 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04197453 live on ClinicalTrials.gov.