MitraClip REPAIR MR Study
Public ClinicalTrials.gov record NCT04198870. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Percutaneous MitraClip Device or Surgical Mitral Valve REpair in PAtients With PrImaRy MItral Regurgitation Who Are Candidates for Surgery (REPAIR MR)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this randomized controlled trial (RCT) is to compare the clinical outcome of MitraClip™ device versus surgical repair in patients with severe primary MR who are at moderate surgical risk and whose mitral valve has been determined to be suitable for correction by MV repair surgery by the cardiac surgeon on the local site heart team.
Study identification
- NCT ID
- NCT04198870
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 500 participants
Conditions and interventions
Conditions
Interventions
- MitraClip™ device implantation Device
- Mitral Valve Repair Surgery Procedure
Device · Procedure
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 21, 2020 (Actual)
- Primary completion
- Dec 2027 (Estimated)
- Completion
- Dec 2035 (Estimated)
- Last update posted
- May 15, 2026
2020 – 2035
United States locations
- U.S. sites
- 63
- U.S. states
- 25
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University Hospital - Univ. of Alabama at Birmingham (UAB) | Birmingham | Alabama | 35249 | — |
| Cardiology Associates of Mobile, Inc. | Mobile | Alabama | 36608 | — |
| Banner-University Medical Center Phoenix | Phoenix | Arizona | 85006 | — |
| St. Josephs Hospital and Medical Center | Phoenix | Arizona | 85013 | — |
| Arizona Cardiovascular Research Center | Phoenix | Arizona | 85016 | — |
| Tucson Medical Center | Tucson | Arizona | 85712 | — |
| Scripps Health | La Jolla | California | 92037 | — |
| Sutter Medical Center, Sacramento | Sacramento | California | 95816 | — |
| University of California - Davis Medical Center | Sacramento | California | 95817 | — |
| Mercy General Hospital | Sacramento | California | 95819 | — |
| University of California at San Francisco | San Francisco | California | 94143 | — |
| Stanford University Medical Center | Stanford | California | 94305 | — |
| Los Robles Regional Medical Center | Thousand Oaks | California | 91360 | — |
| Saint Joseph Hospital | Denver | Colorado | 80218 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 06510 | — |
| Baptist Medical Center | Jacksonville | Florida | 32207 | — |
| NCH Healthcare System | Naples | Florida | 34102 | — |
| Piedmont Heart Institute | Atlanta | Georgia | 30309 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | — |
| Prairie Education & Research Cooperative | Springfield | Illinois | 62701 | — |
| Ascension St. Vincent | Indianapolis | Indiana | 46240 | — |
| Kansas University Medical Center | Kansas City | Kansas | 66160 | — |
| Via Christi Regional Medical Center - St. Francis Campus | Wichita | Kansas | 67214 | — |
| Cardiovascular Research Institute of Kansas | Wichita | Kansas | 67226 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| University of Michigan Medical Center | Ann Arbor | Michigan | 48104 | — |
| Henry Ford Health | Detroit | Michigan | 48202 | — |
| Beaumont Hospital, Royal Oak | Royal Oak | Michigan | 48073 | — |
| Abbott Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Cooper University Hospital | Camden | New Jersey | 08103 | — |
| Morristown Medical Center | Morristown | New Jersey | 07962 | — |
| Jersey Shore University Medical Center | Neptune City | New Jersey | 07753 | — |
| Albany Medical Center | Albany | New York | 12208 | — |
| South Shore University Hospital | Bay Shore | New York | 11706 | — |
| NYU Langone Health | New York | New York | 10016 | — |
| New York-Presbyterian/Columbia University Medical Center | New York | New York | 10032 | — |
| Rochester Regional Health | Rochester | New York | 14617 | — |
| St. Francis Hospital | Roslyn | New York | 11576 | — |
| Mission Health & Hospitals | Asheville | North Carolina | 28801 | — |
| Carolinas Medical Center | Charlotte | North Carolina | 28203 | — |
| Duke University Medical Center | Durham | North Carolina | 27705 | — |
| Christ Hospital | Cincinnati | Ohio | 45219 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Mt. Carmel East | Columbus | Ohio | 43213 | — |
| Integris Baptist Medical Center | Oklahoma City | Oklahoma | 73112 | — |
| Pinnacle Health Cardiovascular Institute, Inc. | Harrisburg | Pennsylvania | 17105 | — |
| Allegheny General Hospital - ASRI | Pittsburgh | Pennsylvania | 15212 | — |
| UPMC | Pittsburgh | Pennsylvania | 15213 | — |
| Lankenau Institute for Medical Research | Wynnewood | Pennsylvania | 19096 | — |
| TriStar Centennial Medical Center | Nashville | Tennessee | 37203 | — |
| Ascension Saint Thomas | Nashville | Tennessee | 37205 | — |
| Vanderbilt Heart & Vascular Institute | Nashville | Tennessee | 37232 | — |
| Ascension Texas Cardiovascular Research | Austin | Texas | 78705 | — |
| HCA Houston Healthcare Medical Center | Houston | Texas | 77004 | — |
| UTHealth Memorial Hermann | Houston | Texas | 77008 | — |
| Houston Methodist | Houston | Texas | 77030 | — |
| Intermountain Medical Center | Murray | Utah | 84157 | — |
| University of Virginia Medical Center | Charlottesville | Virginia | 22908 | — |
| Sentara Norfolk General Hospital | Norfolk | Virginia | 23507 | — |
| Swedish Medical Center | Seattle | Washington | 98107 | — |
| The Heart Institute at Virginia Mason | Seattle | Washington | 98111 | — |
| West Virginia University Hospital | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04198870, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 15, 2026 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04198870 live on ClinicalTrials.gov.