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Terminated Phase 3 Interventional Results available

Safety and Effectiveness of Nabiximols Oromucosal Spray as Add-on Therapy in Participants With Spasticity Due to Multiple Sclerosis

ClinicalTrials.gov ID: NCT04203498

Public ClinicalTrials.gov record NCT04203498. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 8, 2026, 7:56 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Double-blind, Randomized, Placebo-controlled, Parallel-group Trial of the Efficacy and Safety of Nabiximols Oromucosal Spray as Add-on Therapy in Patients With Spasticity Due to Multiple Sclerosis

Study identification

NCT ID
NCT04203498
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Jazz Pharmaceuticals
Industry
Enrollment
139 participants

Conditions and interventions

Interventions

  • Nabiximols Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 30, 2020
Primary completion
Feb 9, 2023
Completion
Feb 27, 2023
Last update posted
May 7, 2024

2020 – 2023

United States locations

U.S. sites
15
U.S. states
11
U.S. cities
14
Facility City State ZIP Site status
University of Alabama at Birmingham School of Medicine Birmingham Alabama 35233
Neurostudies - Port Charlotte Port Charlotte Florida 33952
University of South Florida Tampa Florida 33613
Accel Research Sites - Enterprise Tampa Florida 33634
Shepherd Center Atlanta Georgia 30309
Consultants in Neurology - Northbrook Northbrook Illinois 60062
American Health Network of Indiana Avon Indiana 46123
Ochsner Medical Center New Orleans Louisiana 70121
The Multiple Sclerosis Center For Innovations In Care St Louis Missouri 63131
Raleigh Neurology Associates - Raleigh Location Raleigh North Carolina 27607
University of Cincinnati (UC) Health Dayton Ohio 45417
Neurology Clinic - Cordova Cordova Tennessee 38018
Hope Neurology Knoxville Tennessee 37922
University of Texas Southwestern Medical Center Dallas Texas 75390
Central Texas Neurology Consultants Round Rock Texas 78681

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 22 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04203498, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 7, 2024 · Synced May 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04203498 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →