Safety and Effectiveness of Nabiximols Oromucosal Spray as Add-on Therapy in Participants With Spasticity Due to Multiple Sclerosis
Public ClinicalTrials.gov record NCT04203498. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-blind, Randomized, Placebo-controlled, Parallel-group Trial of the Efficacy and Safety of Nabiximols Oromucosal Spray as Add-on Therapy in Patients With Spasticity Due to Multiple Sclerosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This trial is being conducted to demonstrate the efficacy of nabiximols, compared with placebo, when added to standard of care, in the treatment of muscle spasms associated with multiple sclerosis (MS).
Study identification
- NCT ID
- NCT04203498
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 139 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 1, 2020 (Actual)
- Primary completion
- Feb 10, 2023 (Actual)
- Completion
- Feb 28, 2023 (Actual)
- Last update posted
- May 8, 2024
2020 – 2023
United States locations
- U.S. sites
- 15
- U.S. states
- 11
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham School of Medicine | Birmingham | Alabama | 35233 | — |
| Neurostudies - Port Charlotte | Port Charlotte | Florida | 33952 | — |
| University of South Florida | Tampa | Florida | 33613 | — |
| Accel Research Sites - Enterprise | Tampa | Florida | 33634 | — |
| Shepherd Center | Atlanta | Georgia | 30309 | — |
| Consultants in Neurology - Northbrook | Northbrook | Illinois | 60062 | — |
| American Health Network of Indiana | Avon | Indiana | 46123 | — |
| Ochsner Medical Center | New Orleans | Louisiana | 70121 | — |
| The Multiple Sclerosis Center For Innovations In Care | St Louis | Missouri | 63131 | — |
| Raleigh Neurology Associates - Raleigh Location | Raleigh | North Carolina | 27607 | — |
| University of Cincinnati (UC) Health | Dayton | Ohio | 45417 | — |
| Neurology Clinic - Cordova | Cordova | Tennessee | 38018 | — |
| Hope Neurology | Knoxville | Tennessee | 37922 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Central Texas Neurology Consultants | Round Rock | Texas | 78681 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 22 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04203498, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 8, 2024 · Synced Oct 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04203498 live on ClinicalTrials.gov.