Study of Aldafermin (NGM282) in Subjects With Compensated Cirrhosis (ALPINE 4)
Public ClinicalTrials.gov record NCT04210245. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Evaluation of Efficacy, Safety and Tolerability of NGM282 (Aldafermin) in a Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center Study in Subjects With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (ALPINE 4)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A multi-center evaluation of aldafermin in a randomized, double-blind, placebo-controlled study in subjects with compensated cirrhosis.
Study identification
- NCT ID
- NCT04210245
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 160 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 23, 2020 (Actual)
- Primary completion
- Jan 4, 2023 (Actual)
- Completion
- Feb 23, 2023 (Actual)
- Last update posted
- Mar 26, 2025
2020 – 2023
United States locations
- U.S. sites
- 31
- U.S. states
- 15
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| NGM Clinical Study Site | Glendale | Arizona | 85306 | — |
| NGM Clinical Study Site 413 | Tucson | Arizona | 85711 | — |
| NGM Clinical Study Site 415 | Tucson | Arizona | 85711 | — |
| NGM Clinical Study Site | North Little Rock | Arkansas | 72117 | — |
| NGM Clinical Study Site | Fresno | California | 93720 | — |
| NGM Clinical Study Site | La Jolla | California | 92037 | — |
| NGM Clinical Study Site | Los Angeles | California | 90057 | — |
| NGM Clinical Study Site | Panorama City | California | 91402 | — |
| NGM Clinical Study Site | Rialto | California | 92377 | — |
| NGM Clinical Study Site | Boca Raton | Florida | 33434 | — |
| NGM Clinical Study Site | Miami | Florida | 33136 | — |
| NGM Clinical Study Site | Marietta | Georgia | 30060 | — |
| NGM Clinical Study Site | Chicago | Illinois | 60611 | — |
| NGM Clinical Study Site | Chicago | Illinois | 60637 | — |
| NGM Clinical Study Site | Baltimore | Maryland | 21202 | — |
| NGM Clinical Study Site | Boston | Massachusetts | 02111 | — |
| NGM Clinical Study Site | Boston | Massachusetts | 02114 | — |
| NGM Clinical Study Site | Flowood | Mississippi | 39232 | — |
| NGM Clinical Study Site 488 | Jackson | Mississippi | 39216 | — |
| NGM Clinical Study Site | Kansas City | Missouri | 64131 | — |
| NGM Clinical Study Site | Durham | North Carolina | 27710 | — |
| NGM Clinical Study Site | Germantown | Tennessee | 38138 | — |
| NGM Clinical Study Site | Austin | Texas | 78746 | — |
| NGM Clinical Study Site | Edinburg | Texas | 78229 | — |
| NGM Clinical Study Site | Edinburg | Texas | 78539 | — |
| NGM Clinical Study Site 481 | Houston | Texas | 77030 | — |
| NGM Clinical Study Site | San Antonio | Texas | 78215 | — |
| NGM Clinical Study Site | San Antonio | Texas | 78229 | — |
| NGM Clinical Study Site | Richmond | Virginia | 23249 | — |
| NGM Clinical Study Site | Richmond | Virginia | 23298 | — |
| NGM Clinical Study Site 482 | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 18 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04210245, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 26, 2025 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04210245 live on ClinicalTrials.gov.