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Completed Phase 2 Interventional Results available

Study of Semaglutide for Non-Alcoholic Fatty Liver Disease (NAFLD), a Metabolic Syndrome With Insulin Resistance, Increased Hepatic Lipids, and Increased Cardiovascular Disease Risk (The SLIM LIVER Study)

ClinicalTrials.gov ID: NCT04216589

Public ClinicalTrials.gov record NCT04216589. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 9:56 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Single-Arm, Open-Label, Pilot Study of Semaglutide for Non-Alcoholic Fatty Liver Disease (NAFLD), a Metabolic Syndrome With Insulin Resistance, Increased Hepatic Lipids, and Increased Cardiovascular Disease Risk (The SLIM LIVER Study)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study was to evaluate the effects of semaglutide on intra-hepatic triglyceride (IHTG) content in people living with HIV (PLWH), central adiposity, insulin resistance or pre-diabetes, and hepatic steatosis.

Study identification

NCT ID
NCT04216589
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
51 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 18, 2021
Primary completion
Mar 15, 2023
Completion
Sep 14, 2023
Last update posted
Sep 30, 2024

2021 – 2023

United States locations

U.S. sites
8
U.S. states
7
U.S. cities
8
Facility City State ZIP Site status
Alabama CRS (Site ID: 31788) Birmingham Alabama 35294
University of Colorado Hospital CRS (Site ID: 6101) Aurora Colorado 80045
Johns Hopkins University CRS Baltimore Maryland 21287
Massachusetts General Hospital CRS (MGH CRS) (Site ID: 101) Boston Massachusetts 02114
Cincinnati Clinical Research Site (Site ID: 2401) Cincinnati Ohio 45267-0405
Ohio State University CRS (Site ID: 2301) Columbus Ohio 43210
Houston AIDS Research Team CRS (Site ID: 31473) Houston Texas 77009
University of Washington AIDS CRS (Site ID: 1401) Seattle Washington 98104-9929

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

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About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04216589, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 30, 2024 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04216589 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →