A Study to Test the Combination of Tiotropium and Olodaterol Using the Respimat® Inhaler in People With Chronic Obstructive Pulmonary Disease (COPD) Who Have Different Abilities to Inhale
Public ClinicalTrials.gov record NCT04223843. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Multi-center, Parallel Group Study to Compare the Efficacy of Inhaled Tiotropium + Olodaterol, Fixed Dose Combination (5 mcg/5mcg) vs. Placebo Delivered by Respimat Inhaler in Patients With Moderate to Severe COPD, Stratified by Peak Inspiratory Flow Rate [TRONARTO].
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To demonstrate the efficacy of inhaled tiotropium + olodaterol via Respimat® on lung function in patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD) with optimal and sub-optimal Peak Inspiratory Flow Rate (PIFR). Disease severity (moderate to severe) is based on the Global Initiative for Chronic Lung Disease (GOLD) guidelines (GOLD 2 - 3)
Study identification
- NCT ID
- NCT04223843
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 213 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 8, 2020 (Actual)
- Primary completion
- Sep 7, 2020 (Actual)
- Completion
- Sep 29, 2020 (Actual)
- Last update posted
- Nov 18, 2021
2020
United States locations
- U.S. sites
- 21
- U.S. states
- 12
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| SEC Lung | Andalusia | Alabama | 36420 | — |
| Jasper Summit Research, LLC | Jasper | Alabama | 35501 | — |
| Meris Clinical Research | Brandon | Florida | 33511 | — |
| Clinical Research of West Florida, Inc. | Clearwater | Florida | 33765 | — |
| Clinical Research Specialists LLC | Kissimmee | Florida | 34746 | — |
| Clinical Research of West Florida, Inc. | Tampa | Florida | 33606 | — |
| Best Clinical Trials, LLC | New Orleans | Louisiana | 70115 | — |
| Infinity Medical Research | North Dartmouth | Massachusetts | 02747 | — |
| Pulmonary Rsrch Inst of SE MI | Farmington Hills | Michigan | 48152 | — |
| Minnesota Lung Center and Sleep Institute | Edina | Minnesota | 55435 | — |
| Minnesota Lung Center | Woodbury | Minnesota | 55125 | — |
| Valley Regional Hospital | Claremont | New Hampshire | 03743 | — |
| CHEAR Center LLC | The Bronx | New York | 10455 | — |
| North Carolina Clinical Research | Raleigh | North Carolina | 27607 | — |
| Southeastern Research Center | Winston-Salem | North Carolina | 27103 | — |
| Bernstein Clinical Rsrch Ctr | Cincinnati | Ohio | 45231 | — |
| Lowcountry Lung and Critical Care | Charleston | South Carolina | 29406 | — |
| Carolina Medical Research | Clinton | South Carolina | 29325 | — |
| VitaLink Research -Gaffney | Gaffney | South Carolina | 29340 | — |
| Vitalink Research - Spartansburg | Spartanburg | South Carolina | 29303 | — |
| Diagnostics Research Group | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04223843, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 18, 2021 · Synced Oct 28, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04223843 live on ClinicalTrials.gov.