LIFE-BTK Randomized Controlled Trial
Public ClinicalTrials.gov record NCT04227899. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
LIFE-BTK (pivotaL Investigation of saFety and Efficacy of BRS Treatment-Below The Knee) Randomized Controlled Trial
Study identification
- NCT ID
- NCT04227899
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Lead sponsor
- Abbott Medical Devices
- Industry
- Enrollment
- 261 participants
Conditions and interventions
Conditions
Interventions
- Esprit BTK Device Device
- Percutaneous Transluminal Angioplasty (PTA) Device Device
Device
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 17, 2020
- Primary completion
- Aug 16, 2023
- Completion
- Jun 30, 2027
- Last update posted
- Dec 29, 2025
2020 – 2027
United States locations
- U.S. sites
- 43
- U.S. states
- 22
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Comprehensive Integrated Care | Gilbert | Arizona | 85233 | — |
| Arkansas Heart Hospital | Little Rock | Arkansas | 72211 | — |
| St. Helena Hospital | Deer Park | California | 94574 | — |
| Mission Cardiovascular Research Institute | Fremont | California | 94538 | — |
| UCSF Fresno | Fresno | California | 93701 | — |
| St. Joseph Hospital | Orange | California | 92868 | — |
| University of Colorado Hospital | Aurora | Colorado | 80045 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 06510 | — |
| Manatee Memorial Hospital | Bradenton | Florida | 34208 | — |
| First Coast Cardiovascular Institute | Jacksonville | Florida | 32218 | — |
| Palm Vascular Centers | Miami Beach | Florida | 33140 | — |
| Tallahassee Research Institute | Tallahassee | Florida | 32308 | — |
| Piedmont Heart Institute | Atlanta | Georgia | 30309 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| The Iowa Clinic | West Des Moines | Iowa | 50266 | — |
| Via Christi Regional Medical Center - St. Francis Campus | Wichita | Kansas | 67226 | — |
| Cardiovascular Institute of the South | Houma | Louisiana | 70360 | — |
| St. Elizabeth's Medical Center | Boston | Massachusetts | 02135 | — |
| Charlton Memorial Hospital | Russells Mills | Massachusetts | 02720 | — |
| Jackson Heart Clinic | Jackson | Mississippi | 39216 | — |
| Deborah Heart & Lung Center | Browns Mills | New Jersey | 08015 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Vascular Institute of Atlantic Medical Imaging | Pomona | New Jersey | 08240 | — |
| Holy Name Medical Center | Teaneck | New Jersey | 07666 | — |
| NYU Langone Health | New York | New York | 10016 | — |
| Mount Sinai Hospital | New York | New York | 10029 | — |
| New York-Presbyterian/Columbia University Medical Center | New York | New York | 10032 | — |
| New York Presbyterian Hospital/Cornell University | New York | New York | 10065 | — |
| James J. Peters VA Medical Center | The Bronx | New York | 10468 | — |
| NC Heart & Vascular Research | Raleigh | North Carolina | 27607 | — |
| The Lindner Center | Cincinnati | Ohio | 45255 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ascension St. John Jane Phillips | Bartlesville | Oklahoma | 74006 | — |
| Lankenau Institute for Medical Research | Bryn Mawr | Pennsylvania | 19096 | — |
| Saint Vincent Consultants in Cardiovascular Diseases | Erie | Pennsylvania | 16502 | — |
| Pinnacle Health System | Wormleysburg | Pennsylvania | 17043 | — |
| Anmed Health | Anderson | South Carolina | 29621 | — |
| Wellmont CVA Heart Institute | Kingsport | Tennessee | 37660 | — |
| University of Texas Southwestern Medical Center at Dallas | Dallas | Texas | 75390 | — |
| Baylor All Saints Medical Center at Fort Worth | Fort Worth | Texas | 76104 | — |
| Texas Tech University Health Sciences Center at Lubbock | Lubbock | Texas | 79430 | — |
| San Antonio Vascular and Endovascular Clinic | San Antonio | Texas | 78221 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04227899, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 29, 2025 · Synced May 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04227899 live on ClinicalTrials.gov.