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Completed Phase 3 Interventional Results available

Study of Cingal® and Triamcinolone Hexacetonide for the Relief of Knee Osteoarthritis Pain

ClinicalTrials.gov ID: NCT04231318

Public ClinicalTrials.gov record NCT04231318. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 4:17 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo Controlled, Multi-Center Study of a Single Injection Cross-Linked Sodium Hyaluronate Combined With Triamcinolone Hexacetonide (Cingal®) to Provide Symptomatic Relief of Osteoarthritis of the Knee

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a multi-center, randomized, double-blind, parallel group, placebo controlled trial to compare the safety and effectiveness of a single injection of Cingal® to a single injection of Triamcinolone Hexacetonide (TH) to achieve pain relief and other symptoms of osteoarthritis of the knee.

Study identification

NCT ID
NCT04231318
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Anika Therapeutics, Inc.
Industry
Enrollment
231 participants

Conditions and interventions

Eligibility (public fields only)

Age range
40 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 10, 2020
Primary completion
May 15, 2022
Completion
May 15, 2022
Last update posted
Aug 8, 2023

2020 – 2022

United States locations

U.S. sites
26
U.S. states
10
U.S. cities
24
Facility City State ZIP Site status
Orthopaedic Specialist of North America, PLLC DBA OrthoArizona Chandler Arizona 85224
Valley Bone and Joint Specialists Chandler Arizona 85224
Tucson Orthopaedic Institute Tucson Arizona 85712
Advanced Research Center, Inc. Anaheim California 92805
Medvin Clinical Research Covina California 91722
Core Orthopaedic Medical Center (San Dieguito Orthopedic Medical Center) Encinitas California 92024
Infinity Clinical Research Norco California 92860
Dream Team Clinical Research Pomona California 91767
Probe Clinical Research Corporation Riverside California 92501
Artemis Institute for Clinical Research, Riverside Riverside California 92503
Artemis Institute for Clinical Research, San Marcos Summerville California 29485
Medvin Clinical Research Tujunga California 91042
Medvin Clinical Research Whittier California 90602
Tampa Bay Medical Research Inc Clearwater Florida 33761
Shrock Research Fort Lauderdale Florida 33316
Pines Clinical Research, Inc Hollywood Florida 33024
Ascension Research Pinellas Park Florida 33781
Precision Clinical Research, LLC Sunrise Florida 33351
Northwestern University Feinberg School of Medicine Chicago Illinois 60611
Best Clinical Trials, LLC New Orleans Louisiana 70115
Anika Therapeutics Bedford Massachusetts 01730
Upstate Clinical Research Associates, LLC Williamsville New York 14221
PMG Research of Wilmington, LLC Wilmington North Carolina 28403
Coastal Carolina Research Center (CCRC) Mt. Pleasant South Carolina 29464-3803
Palmetto Clinical Research Summerville South Carolina 29485
Spectrum Medical, Inc. Danville Virginia 24541

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04231318, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 8, 2023 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04231318 live on ClinicalTrials.gov.

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