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Completed No phase listed Observational Accepts healthy volunteers

Physical Resilience: Indicators and Mechanisms in the Elderly (PRIME) Collaborative Phase 2

ClinicalTrials.gov ID: NCT04235309

Public ClinicalTrials.gov record NCT04235309. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 9, 2026, 1:10 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to examine underlying physical resilience (the ability to bounce back) in response to a specific stressor (total knee replacement).

Study identification

NCT ID
NCT04235309
Recruitment status
Completed
Study type
Observational
Phase
Not listed
Lead sponsor
Duke University
Other
Enrollment
297 participants

Conditions and interventions

Interventions

Not listed

Eligibility (public fields only)

Age range
60 Years and older
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 27, 2020 (Actual)
Primary completion
Oct 30, 2023 (Actual)
Completion
Oct 30, 2023 (Actual)
Last update posted
Dec 8, 2025

2020 – 2023

United States locations

U.S. sites
3
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
Duke Regional Hospital Durham North Carolina 27704 —
Duke University Hospital Durham North Carolina 27710 —
Duke University Medical Center Durham North Carolina 27710 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04235309, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 8, 2025 · Synced Oct 9, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04235309 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →