ACX-362E [Ibezapolstat] for Oral Treatment of Clostridioides Difficile Infection
Public ClinicalTrials.gov record NCT04247542. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
ACX-362E [Ibezapolstat] for Oral Treatment of Clostridioides Difficile Infection: A Phase 2A Open-Label Segment Followed by a Phase 2B Double-Blind Vancomycin-Controlled Segment
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Segments 2A and 2B of this trial evaluate the safety, efficacy, pharmacokinetics, fecal concentrations, and fecal microbiome effects of ACX-362E \[ibezapolstat\] in patients with C. difficile infection (CDI).
Study identification
- NCT ID
- NCT04247542
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 53 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 6, 2020 (Actual)
- Primary completion
- Oct 3, 2023 (Actual)
- Completion
- Nov 15, 2023 (Actual)
- Last update posted
- Jan 17, 2025
2020 – 2023
United States locations
- U.S. sites
- 29
- U.S. states
- 13
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Acurx Site #118: Dr Janet Reiser | Scottsdale | Arizona | 85251 | — |
| Acurx Site #115: Dr Neera Grover | Apple Valley | California | 92307 | — |
| Acurx Site #125: Dr Karen Simon | Camarillo | California | 93012 | — |
| Acurx Site #111: Dr Jatinder Pruthi | Lancaster | California | 93534 | — |
| Acurx Site #131: Dr Michael Jardula | Palm Springs | California | 92262 | — |
| Acurx Site #129: Dr Stuart Cohen | Sacramento | California | 95817 | — |
| Acurx Site #105 | Doral | Florida | 33166 | — |
| Acurx Site #122: Dr Faride Ramos | Doral | Florida | 33172 | — |
| Acurx Site #101: Dr Idalia Acosta | Miami | Florida | 33015 | — |
| Acurx Site #124: Dr Yunior Silva-Barrero | Miami | Florida | 33125 | — |
| Acurx Site #108: Dr Idania Garcia Del Sol | Miami | Florida | 33142 | — |
| Acurx Site #116: Dr Erick Juarez | Miami | Florida | 33155 | — |
| Acurx Site #119: Dr Jorge Paoli-Bruno | Miami | Florida | 33186 | — |
| Acurx Site #107: Dr Belkis Delgado | Miami Springs | Florida | 33166 | — |
| Acurx Site #117: Dr Rafael Companioni | Panama City | Florida | 32405 | — |
| Acurx Site #102: Dr Richard Nathan | Idaho Falls | Idaho | 83404 | — |
| Acurx Site #123: Dr Harry Schrager | Newton | Massachusetts | 02462 | — |
| Acurx Site #104: Dr JeanMarie Houghton | Worcester | Massachusetts | 01655 | — |
| Acurx Site #103: Dr John Pullman | Butte | Montana | 59701 | — |
| Acurx Site #130: Dr Michael DiGiovanna | North Massapequa | New York | 11758 | — |
| Acurx Site #127: Dr Christopher Connolley | Winston-Salem | North Carolina | 27103 | — |
| Acurx Site #126: Dr Andrew Pearson | Myrtle Beach | South Carolina | 29572 | — |
| Acurx Site #114: Dr Eugene Ryan | Chattanooga | Tennessee | 37404 | — |
| Acurx Site #121: Dr Ramesh Gowrappala | Houston | Texas | 77024 | — |
| Acurx Site #120: Dr Vanna Gold | Lampasas | Texas | 76550 | — |
| Acurx Site #113: Dr Jennifer Vincent | Temple | Texas | 76508 | — |
| Acurx Site #110: Dr Val Hansen | Bountiful | Utah | 84010 | — |
| Acurx Site #106: Dr Bezawit Tekola | Fairfax | Virginia | 22031 | — |
| Acurx Site #109: Dr Robert Brennan | Lynchburg | Virginia | 24501 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04247542, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 17, 2025 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04247542 live on ClinicalTrials.gov.