A Study on Impact of Canagliflozin on Health Status, Quality of Life, and Functional Status in Heart Failure
Public ClinicalTrials.gov record NCT04252287. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Canagliflozin: Impact on Health Status, Quality of Life, and Functional Status in Heart Failure
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the superiority of the effectiveness of canagliflozin 100 milligram (mg) daily versus placebo in participants with symptomatic heart failure (HF) in improving the overall Kansas City Cardiomyopathy Questionnaire (KCCQ) Total Symptom Score (TSS).
Study identification
- NCT ID
- NCT04252287
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 476 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 10, 2020 (Actual)
- Primary completion
- Nov 9, 2021 (Actual)
- Completion
- Nov 9, 2021 (Actual)
- Last update posted
- Mar 30, 2025
2020 – 2021
United States locations
- U.S. sites
- 18
- U.S. states
- 14
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mercy Clinic Cardiology - Fort Smith | Fort Smith | Arkansas | 72903 | — |
| University of Colorado Anschutz Medical Campus | Aurora | Colorado | 80045 | — |
| Clearwater Cardiovascular Consultants | Clearwater | Florida | 33756 | — |
| Emory University | Atlanta | Georgia | 30022 | — |
| St Lukes Regional Medical | Boise | Idaho | 83712 | — |
| OSF HealthCare Cardiovascular Institute | Peoria | Illinois | 61614 | — |
| Central Dupage Hospital | Winfield | Illinois | 60190 | — |
| Parkview Cancer Institute | Fort Wayne | Indiana | 46845 | — |
| University of Kansas Medical Center Research Institute | Kansas City | Kansas | 66160 | — |
| MedStar Health Research Institute | Hyattsville | Maryland | 20782 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| St. Luke's Hospital Kansas City | Kansas City | Missouri | 64111 | — |
| Mercy Health Research | Washington | Missouri | 63090 | — |
| Robert Wood Johnson Medical School Dept. of Medicine | Piscataway | New Jersey | 08854 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Thomas Spann Clinic | Corpus Christi | Texas | 78412 | — |
| Texas Heart Institute | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04252287, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 30, 2025 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04252287 live on ClinicalTrials.gov.