A Study to Investigate the Efficacy and Safety of RG7774 in Patients With Diabetes Mellitus Type 1 or Type 2 With Treatment-Naive Diabetic Retinopathy
Public ClinicalTrials.gov record NCT04265261. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Randomized, Double-Masked, 48-Week, Parallel-Group, Placebo-Controlled, Proof-of-Concept Study to Investigate the Efficacy and Safety of RG7774 in Patients With Diabetes Mellitus Type 1 or Type 2 With Treatment-Naive Diabetic Retinopathy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The study's main purpose is to asses the safety, tolerability, and effect of oral administration of RG7774 on the severity of diabetic retinopathy (DR) in participants with moderately severe to severe non-proliferative diabetic retinopathy (NPDR) and good vision.
Study identification
- NCT ID
- NCT04265261
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 139 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 5, 2020 (Actual)
- Primary completion
- Jul 19, 2023 (Actual)
- Completion
- Jul 19, 2023 (Actual)
- Last update posted
- Sep 25, 2024
2020 – 2023
United States locations
- U.S. sites
- 37
- U.S. states
- 20
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Retina and Vitreous Consultants | Phoenix | Arizona | 85016 | — |
| Retina Associates Tucson | Tucson | Arizona | 85710 | — |
| Win Retina | Arcadia | California | 91006 | — |
| Global Research Management | Glendale | California | 91204 | — |
| Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | Torrance | California | 90502 | — |
| Retina Consultants of Southern Colorado PC | Colorado Springs | Colorado | 80909 | — |
| Retina Group of New England | Waterford | Connecticut | 06385 | — |
| Rand Eye | Deerfield Beach | Florida | 33064 | — |
| Florida Retina Consultants | Lakeland | Florida | 33805 | — |
| Florida Eye Associates | Melbourne | Florida | 32901 | — |
| Medeye Associates | Miami | Florida | 33143 | — |
| Retina Specialty Institute | Pensacola | Florida | 32503 | — |
| Retina Vitreous Assoc of FL | St. Petersburg | Florida | 33711 | — |
| Southeast Retina Center | Augusta | Georgia | 30909 | — |
| Marietta Eye Clinic | Marietta | Georgia | 30060 | — |
| Retina Associated Ltd | Elmhurst | Illinois | 60126 | — |
| University Retina and Macula Associates, PC | Oak Forest | Illinois | 60452 | — |
| Cumberland Valley Retina PC | Hagerstown | Maryland | 21740 | — |
| University of Michigan, Kellogg Eye Center | Ann Arbor | Michigan | 48105 | — |
| Deep Blue Retina PLLC | Southaven | Mississippi | 38671 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| Envision Ocular, LLC | Bloomfield | New Jersey | 07003 | — |
| Eye Associates of New Mexico | Albuquerque | New Mexico | 87109 | — |
| Velocity Clinical Research | East Syracuse | New York | 13057 | — |
| Ophthalmic Consultants of Long Island | Oceanside | New York | 11572 | — |
| Charlotte Eye Ear Nose and Throat Associates | Charlotte | North Carolina | 28210 | — |
| EyeHealth Northwest | Portland | Oregon | 97225 | — |
| Erie Retinal Surgery | Erie | Pennsylvania | 16507 | — |
| Charleston Neuroscience Institute | Ladson | South Carolina | 29456 | — |
| Southeastern Retina Associates Chattanooga | Chattanooga | Tennessee | 37421 | — |
| Charles Retina Institute | Germantown | Tennessee | 38138 | — |
| Retina Res Institute of Texas | Abilene | Texas | 79606 | — |
| Austin Clinical Research LLC | Austin | Texas | 78750 | — |
| San Antonio Eye Center | San Antonio | Texas | 78215 | — |
| Retina Consultants of Texas | The Woodlands | Texas | 77384-4167 | — |
| Retinal Consultants of Houston | The Woodlands | Texas | 77384 | — |
| Strategic Clinical Research Group, LLC | Willow Park | Texas | 76087 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 31 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04265261, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 25, 2024 · Synced Nov 6, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04265261 live on ClinicalTrials.gov.