Study to Evaluate Patients With Cerebrotendinous Xanthomatosis (RESTORE)
Public ClinicalTrials.gov record NCT04270682. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Study to Evaluate the Effects of Chenodeoxycholic Acid in Adult and Pediatric Patients With Cerebrotendinous Xanthomatosis
Study identification
- NCT ID
- NCT04270682
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Mirum Pharmaceuticals, Inc.
- Industry
- Enrollment
- 19 participants
Conditions and interventions
Conditions
Interventions
- Blinded CDCA 250 mg TID Drug
- Placebo Drug
- Open-Label CDCA 250 mg TID Drug
- Rescue Medication CDCA 250 mg TID Drug
- CDCA Weight-Based Dose TID Drug
Drug
Eligibility (public fields only)
- Age range
- 1 Month and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 30, 2020
- Primary completion
- Jul 12, 2023
- Completion
- Oct 3, 2023
- Last update posted
- Oct 27, 2024
2020 – 2023
United States locations
- U.S. sites
- 9
- U.S. states
- 8
- U.S. cities
- 8
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Travere Investigational Site | Aurora | Colorado | 80045 | — |
| Travere Investigational Site | Orlando | Florida | 32806 | — |
| Travere Investigational Site | Iowa City | Iowa | 52242 | — |
| Travere Investigational Site | New Orleans | Louisiana | 70112 | — |
| Travere Investigational Site | New Orleans | Louisiana | 70121 | — |
| Travere Investigational Site | Great Neck | New York | 11021 | — |
| Travere Investigational Site | Columbus | Ohio | 43221 | — |
| Travere Investigational Site | Austin | Texas | 78723 | — |
| Travere Investigational Site | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04270682, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 27, 2024 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04270682 live on ClinicalTrials.gov.