A Study to Understand Effectiveness and Safety of ABP 938 Compared to Aflibercept (Eylea®) in Patients Suffering With Neovascular Age-related Macular Degeneration [Neovascular (Wet) AMD]
Public ClinicalTrials.gov record NCT04270747. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-masked, Phase 3 Study of ABP 938 Efficacy and Safety Compared to Aflibercept (Eylea®) in Subjects With Neovascular Age-related Macular Degeneration
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare the efficacy and safety of ABP 938 versus Aflibercept (Eylea®) in the treatment of neovascular age-related macular degeneration. Subjects will be randomized in a masked 1:1 ratio to receive 2 mg (0.05 mL) of either ABP 938 (Treatment Group A) or aflibercept (Treatment Group B) administered by intravitreal (IVT) injection.
Study identification
- NCT ID
- NCT04270747
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 576 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 22, 2020 (Actual)
- Primary completion
- Jul 18, 2022 (Actual)
- Completion
- Jan 30, 2023 (Actual)
- Last update posted
- Sep 10, 2025
2020 – 2023
United States locations
- U.S. sites
- 41
- U.S. states
- 19
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Associated Retina Consultants, Ltd. - Research | Phoenix | Arizona | 85020 | — |
| Retina Consultants of Orange County | Fullerton | California | 92835 | — |
| UCSD Shiley Eye Institute, Jacobs Retina Center | La Jolla | California | 92093 | — |
| Jules Stein Eye Institute, UCLA | Los Angeles | California | 90095-7000 | — |
| Southern California Desert Retina Consultants | Palm Desert | California | 92211 | — |
| Retina Consultants San Diego | Poway | California | 92064 | — |
| Retina Consultants of Southern California | Redlands | California | 92374 | — |
| Retinal Consultants Medical Group, Inc. | Sacramento | California | 95825 | — |
| Orange County Retina Medical Group | Santa Ana | California | 92705 | — |
| Miramar Eye Specialists | Ventura | California | 93003 | — |
| Colorado Retina Associates | Lakewood | Colorado | 80228 | — |
| Retina Group of New England | Waterford | Connecticut | 06385 | — |
| Florida Retina Consultants | Lakeland | Florida | 33805 | — |
| Medeye Associates | Miami | Florida | 33143 | — |
| Center for Retina and Macular Disease | Winter Haven | Florida | 33880 | — |
| Southeast Retina Center | Augusta | Georgia | 30909 | — |
| Georgia Retina, P.C. | Marietta | Georgia | 30060 | — |
| Retina Associates IL | Elmhurst | Illinois | 60126 | — |
| Sabates Eye Center | Leawood | Kansas | 66211 | — |
| Retina Associates New Orleans | Metairie | Louisiana | 70006 | — |
| The Retina Care Center | Baltimore | Maryland | 21209 | — |
| Specialty Eye Institute | Jackson | Michigan | 49202 | — |
| Retina Center | Saint Louis Park | Minnesota | 55416 | — |
| Retina Vitreous Surgeons of Central NY, PC | Liverpool | New York | 13088 | — |
| Macula Care | New York | New York | 10021 | — |
| Ophthalmic Consultants of the Capital Region - Ophthalmology | Troy | New York | 12180 | — |
| Charlotte Eye Ear Nose & Throat Associates, P.A. | Charlotte | North Carolina | 28210 | — |
| Sterling Research Group | Cincinnati | Ohio | 45219 | — |
| Eye Care Specialists | Kingston | Pennsylvania | 18704 | — |
| Charleston Neuroscience Institute | Ladson | South Carolina | 29456 | — |
| Black Hills Regional Eye Institute - Ophthalmology | Rapid City | South Dakota | 57701 | — |
| Retina Research Institute of Texas | Abilene | Texas | 79606 | — |
| Retina Consultants of Texas Research Centers | Bellaire | Texas | 77401 | — |
| Texas Retina Associates | Dallas | Texas | 75231 | — |
| Texas Retina Associates | Fort Worth | Texas | 76012 | — |
| Texas Retina Associates | Fort Worth | Texas | 76014 | — |
| Ophthalmology Associates | Fort Worth | Texas | 76102 | — |
| Premiere Retina Specialists | Midland | Texas | 79706 | — |
| Retina Associates of South Texas, P.A. | San Antonio | Texas | 78240-1375 | — |
| Retina Consultants of Houston | The Woodlands | Texas | 77384 | — |
| Strategic Clinical Research | Willow Park | Texas | 76087 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 77 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04270747, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 10, 2025 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04270747 live on ClinicalTrials.gov.