A First-in-Human Study of RPT193 in Healthy Volunteers and Patients With Atopic Dermatitis
Public ClinicalTrials.gov record NCT04271514. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1, Randomized, Double-blind, Placebo-controlled, Single-dose Escalation, Multiple-dose Escalation, and Food Effect Study of RPT193 in Healthy Subjects and Patients With Moderate to Severe Atopic Dermatitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is a first-in-human, 3-part, multi-center, Phase 1, randomized, double-blind, placebo-controlled study with RPT193 in up to 64 healthy male and female subjects and 30 male and female patients with atopic dermatitis. RPT193 is an orally-available, potent, and selective antagonist of CCR4.
Study identification
- NCT ID
- NCT04271514
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 103 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 12, 2019 (Actual)
- Primary completion
- Apr 26, 2021 (Actual)
- Completion
- Apr 26, 2021 (Actual)
- Last update posted
- Sep 30, 2021
2019 – 2021
United States locations
- U.S. sites
- 13
- U.S. states
- 10
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group, LLC | Anniston | Alabama | 36207 | — |
| Perseverance Research Center LLC | Scottsdale | Arizona | 85254 | — |
| University Clinical Trials, Inc | San Diego | California | 92123 | — |
| Lenus Research & Medical Group | Miami | Florida | 33172 | — |
| ForCare Clinical Research | Tampa | Florida | 33613 | — |
| Dawes Fretzin Clinical Research Group, LLC | Indianapolis | Indiana | 46250 | — |
| DelRicht Research | Baton Rouge | Louisiana | 70809 | — |
| Clinical Trials Management,LLC | Metairie | Louisiana | 70006 | — |
| MetroBoston Clinical Partners LLC | Brighton | Massachusetts | 02135 | — |
| Sadick Research Group LLC | New York | New York | 10075 | — |
| Central Sooner Research | Norman | Oklahoma | 73071 | — |
| DermResearch, Inc. | Austin | Texas | 78759 | — |
| Progressive Clinical Research PA | San Antonio | Texas | 78213 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04271514, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 30, 2021 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04271514 live on ClinicalTrials.gov.