ClinicalTrials.gov record
Adaptive COVID-19 Treatment Trial (ACTT)
ClinicalTrials.gov ID: NCT04280705
Public ClinicalTrials.gov record NCT04280705. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Adaptive, Randomized Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Adults
Study identification
- NCT ID
- NCT04280705
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Enrollment
- 1,062 participants
Conditions and interventions
Conditions
Interventions
- Placebo Other
- Remdesivir Drug
Other · Drug
Eligibility (public fields only)
- Age range
- 18 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 20, 2020
- Primary completion
- May 20, 2020
- Completion
- May 20, 2020
- Last update posted
- Mar 13, 2022
2020
United States locations
- U.S. sites
- 41
- U.S. states
- 18
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham School of Medicine - Infectious Disease | Birmingham | Alabama | 35233 | — |
| University of California San Diego Health - Jacobs Medical Center | La Jolla | California | 29037 | — |
| University of California Los Angeles Medical Center - Westwood Clinic | Los Angeles | California | 90095 | — |
| University of California Irvine Medical Center - Infectious Disease | Orange | California | 92868-3298 | — |
| VA Palo Alto Health Care System - Infectious Diseases | Palo Alto | California | 94304-1207 | — |
| University of California Davis Medical Center - Internal Medicine - Infectious Disease | Sacramento | California | 95817-1460 | — |
| Naval Medical Center San Diego - Infectious Disease Clinic | San Diego | California | 92314 | — |
| University of California San Francisco - Zuckerberg San Francisco General Hospital - Division of Human Immunodeficiency Virus, Infectious Disease, and Global Medicine | San Francisco | California | 94110-2859 | — |
| Stanford University - Stanford Hospital and Clinics - Pediatrics - Infectious Diseases | Stanford | California | 94305-2200 | — |
| Cedars Sinai Medical Center | West Hollywood | California | 90048-1804 | — |
| Denver Health Division of Hospital Medicine - Main Campus | Denver | Colorado | 80204 | — |
| Emory Vaccine Center - The Hope Clinic | Decatur | Georgia | 30030-1705 | — |
| Northwestern Hospital - Infectious Disease | Chicago | Illinois | 60611-2908 | — |
| University of Illinois at Chicago College of Medicine - Division of Infectious Diseases | Chicago | Illinois | 60612 | — |
| Southeast Louisiana Veterans Health Care System - Section of Infectious Diseases | New Orleans | Louisiana | 70119 | — |
| University of Maryland School of Medicine - Center for Vaccine Development - Baltimore | Baltimore | Maryland | 21201-1509 | — |
| Johns Hopkins Hospital - Medicine - Infectious Diseases | Baltimore | Maryland | 21287-0005 | — |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20889 | — |
| National Institutes of Health - Clinical Center, National Institute of Allergy and Infectious Diseases Laboratory Of Immunoregulation, Clinical Research Section | Bethesda | Maryland | 20892-1504 | — |
| Massachusetts General Hospital - Infectious Diseases | Boston | Massachusetts | 02114-2621 | — |
| University of Massachusetts Medical School - Infectious Diseases and Immunology | Worcester | Massachusetts | 01655-0002 | — |
| University of Minnesota Medical Center, Fairview - Infectious Diseases and International Medicine | Minneapolis | Minnesota | 55455-0341 | — |
| Saint Louis University - Center for Vaccine Development | St Louis | Missouri | 63104-1015 | — |
| University of Nebraska Medical Center - Infectious Diseases | Omaha | Nebraska | 68105 | — |
| New York University School of Medicine - Langone Medical Center - Microbiology - Parasitology | New York | New York | 10016-6402 | — |
| University of Rochester Medical Center - Vaccine Research Unit | Rochester | New York | 14642-0001 | — |
| Montefiore Medical Center - Infectious Diseases | The Bronx | New York | 10467-2401 | — |
| Duke Human Vaccine Institute - Duke Vaccine and Trials Unit | Durham | North Carolina | 27704 | — |
| Penn State Health Milton S. Hershey Medical Center - Division of Infectious Diseases | Hershey | Pennsylvania | 17033 | — |
| Hospital of the University of Pennsylvania - Infectious Diseases | Philadelphia | Pennsylvania | 19104-4238 | — |
| Vanderbilt University Medical Center - Infectious Diseases | Nashville | Tennessee | 37232-0011 | — |
| Brooke Army Medical Center | Fort Sam Houston | Texas | 78234 | — |
| University of Texas Medical Branch - Division of Infectious Disease | Galveston | Texas | 77555-0435 | — |
| Baylor College of Medicine - Molecular Virology and Microbiology | Houston | Texas | 77030-3411 | — |
| University of Texas Health Science Center at San Antonio - Infectious Diseases | San Antonio | Texas | 78229-3901 | — |
| University of Virginia - Acute Care Surgery | Charlottesville | Virginia | 22908-0816 | — |
| Naval Medical Center Portsmouth - Infectious Disease Division | Portsmouth | Virginia | 23708 | — |
| EvergreenHealth Infectious Disease Service | Kirkland | Washington | 98034 | — |
| The University of Washington - Virology Research Clinic | Seattle | Washington | 98104 | — |
| Providence Sacred Heart Medical Center | Spokane | Washington | 99204 | — |
| Madigan Army Medical Center - Infectious Disease Clinic | Tacoma | Washington | 98431 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 19 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04280705, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 13, 2022 · Synced Jul 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04280705 live on ClinicalTrials.gov.