ClinicalTrials.gov record
HEALEY ALS Platform Trial - Master Protocol
ClinicalTrials.gov ID: NCT04297683
Public ClinicalTrials.gov record NCT04297683. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
HEALEY ALS Platform Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS.
Study identification
- NCT ID
- NCT04297683
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 1,500 participants
Conditions and interventions
Conditions
Interventions
- Zilucoplan Drug
- Verdiperstat Drug
- CNM-Au8 Drug
- Pridopidine Drug
- SLS-005 Trehalose Drug
- ABBV-CLS-7262 Drug
- DNL343 Drug
- NUZ-001 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 13, 2020
- Primary completion
- Jun 30, 2027
- Completion
- Jul 31, 2028
- Last update posted
- Jul 20, 2026
2020 – 2028
United States locations
- U.S. sites
- 81
- U.S. states
- 34
- U.S. cities
- 69
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Mayo Clinic Scottsdale | Scottsdale | Arizona | 85259 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| UC San Diego | La Jolla | California | 92037 | — |
| Loma Linda University Health | Loma Linda | California | 92354 | — |
| Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | 90027 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| University of California, Irvine | Orange | California | 92868 | — |
| Forbes Norris MDA/ALS Research Center, California Pacific Medical Center | San Francisco | California | 94115 | — |
| University of California, San Francisco | San Francisco | California | 94143 | — |
| University of Colorado | Aurora | Colorado | 80045 | — |
| Hospital for Special Care | New Britain | Connecticut | 06053 | — |
| Yale University | New Haven | Connecticut | 06519 | — |
| Georgetown University | Washington D.C. | District of Columbia | 20007 | — |
| George Washington University | Washington D.C. | District of Columbia | 20037 | — |
| Nova Southeastern University | Davie | Florida | 33024 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| Mayo Clinic Florida | Jacksonville | Florida | 32224 | — |
| University of Miami | Miami | Florida | 33136 | — |
| University of South Florida | Tampa | Florida | 33612 | — |
| Augusta University | Augusta | Georgia | 30912 | — |
| Saint Alphonsus Regional Medical Center | Boise | Idaho | 83704 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Indiana University Health | Indianapolis | Indiana | 46202 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| University of Kansas Medical Center | Fairway | Kansas | 66205 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Ochsner Health System | New Orleans | Louisiana | 70115 | — |
| Johns Hopkins University | Baltimore | Maryland | 21205 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Lahey Hospital and Medical Center | Burlington | Massachusetts | 01805 | — |
| University of Massachusetts Medical School | North Worcester | Massachusetts | 01655 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Spectrum Health/Corewell Health | Grand Rapids | Michigan | 49525 | — |
| Essentia Health | Duluth | Minnesota | 55805 | — |
| University of Minnesota Medical School | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55902 | — |
| University of Missouri Health Care | Columbia | Missouri | 65212 | — |
| Saint Louis University | St Louis | Missouri | 63104 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Neurology Associates, P.C./Somnos Clinical Research | Lincoln | Nebraska | 68506 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Dent Neurologic Institute | Amherst | New York | 14226 | — |
| Mount Sinai | New York | New York | 10003 | — |
| Columbia University | New York | New York | 10032 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| Stony Brook University Hospital | Stony Brook | New York | 11794 | — |
| SUNY Upstate | Syracuse | New York | 13202 | — |
| University of North Carolina | Chapel Hill | North Carolina | 27599 | — |
| Atrium Health | Charlotte | North Carolina | 28207 | — |
| Duke University | Durham | North Carolina | 27702 | — |
| Wake Forest Health Science | Winston-Salem | North Carolina | 27157 | — |
| University of Cincinnati | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| The Ohio State University | Columbus | Ohio | 43221 | — |
| OhioHealth Research Institute | Westerville | Ohio | 43082 | — |
| Providence Brain and Spine Institute ALS Center | Portland | Oregon | 97213 | — |
| Lehigh Valley Health Network | Allentown | Pennsylvania | 18103 | — |
| Penn State Hershey | Hershey | Pennsylvania | 17033 | — |
| Jefferson Weinberg ALS Center, Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19107 | — |
| Lewis Katz School of Medicine at Temple University | Philadelphia | Pennsylvania | 19140 | — |
| University of Pittsburg Medical Center | Pittsburgh | Pennsylvania | 15232 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Austin Neuromuscular Clinic | Austin | Texas | 78759 | — |
| Texas Neurology | Dallas | Texas | 75214 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Houston Methodist | Houston | Texas | 77030 | — |
| UTHSCSA | San Antonio | Texas | 78229 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| Virginia Commonwealth University | Henrico | Virginia | 23233 | — |
| Swedish Medical Center | Seattle | Washington | 98122 | — |
| University of Washington | Seattle | Washington | 98195 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04297683, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 20, 2026 · Synced Sep 7, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04297683 live on ClinicalTrials.gov.