ClinicalTrials.gov record
Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer Patients
ClinicalTrials.gov ID: NCT04310020
Public ClinicalTrials.gov record NCT04310020. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Pilot Study of Hypofractionated Radiotherapy Followed by Atezolizumab Consolidation in Stage II or III NSCLC Patients With Borderline Performance Status
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This phase II trial studies the side effects of radiation therapy followed by atezolizumab in treating patients with stage II or III non-small cell lung cancer. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more cancer cells and have fewer side effects. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. The purpose of this study is to test the safety and effectiveness of radiation therapy followed by atezolizumab and find out what side effects, if any, it has on patient's non-small cell lung cancer.
Study identification
- NCT ID
- NCT04310020
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 47 participants
Conditions and interventions
Interventions
- Atezolizumab Drug
- Biospecimen Collection Procedure
- Computed Tomography Procedure
- Hypofractionated Radiation Therapy Radiation
- Magnetic Resonance Imaging Procedure
Drug · Procedure · Radiation
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 12, 2021
- Primary completion
- May 31, 2027
- Completion
- May 31, 2027
- Last update posted
- Aug 23, 2026
2021 – 2027
United States locations
- U.S. sites
- 170
- U.S. states
- 28
- U.S. cities
- 110
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham Cancer Center | Birmingham | Alabama | 35233 | — |
| Anchorage Associates in Radiation Medicine | Anchorage | Alaska | 98508 | — |
| Alaska Breast Care and Surgery LLC | Anchorage | Alaska | 99508 | — |
| Alaska Oncology and Hematology LLC | Anchorage | Alaska | 99508 | — |
| Alaska Women's Cancer Care | Anchorage | Alaska | 99508 | — |
| Katmai Oncology Group | Anchorage | Alaska | 99508 | — |
| Providence Alaska Medical Center | Anchorage | Alaska | 99508 | — |
| NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro | Jonesboro | Arkansas | 72401 | — |
| University of California Davis Comprehensive Cancer Center | Sacramento | California | 95817 | — |
| AdventHealth Porter | Denver | Colorado | 80210 | — |
| AdventHealth Littleton | Littleton | Colorado | 80122 | — |
| AdventHealth Parker | Parker | Colorado | 80138 | — |
| Mount Sinai Comprehensive Cancer Center at Aventura | Aventura | Florida | 33180 | — |
| Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| Augusta University Medical Center | Augusta | Georgia | 30912 | — |
| CTCA at Southeastern Regional Medical Center | Newnan | Georgia | 30265 | — |
| Hawaii Cancer Care Inc - Waterfront Plaza | Honolulu | Hawaii | 96813 | — |
| Island Urology | Honolulu | Hawaii | 96813 | — |
| Queen's Cancer Cenrer - POB I | Honolulu | Hawaii | 96813 | — |
| Queen's Medical Center | Honolulu | Hawaii | 96813 | — |
| Straub Clinic and Hospital | Honolulu | Hawaii | 96813 | — |
| University of Hawaii Cancer Center | Honolulu | Hawaii | 96813 | — |
| Hawaii Cancer Care Inc-Liliha | Honolulu | Hawaii | 96817 | — |
| Queen's Cancer Center - Kuakini | Honolulu | Hawaii | 96817 | — |
| The Cancer Center of Hawaii-Liliha | Honolulu | Hawaii | 96817 | — |
| Kapiolani Medical Center for Women and Children | Honolulu | Hawaii | 96826 | — |
| Wilcox Memorial Hospital and Kauai Medical Clinic | Lihue | Hawaii | 96766 | — |
| Hawaii Cancer Care - Westridge | ‘Aiea | Hawaii | 96701 | — |
| Pali Momi Medical Center | ‘Aiea | Hawaii | 96701 | — |
| Queen's Cancer Center - Pearlridge | ‘Aiea | Hawaii | 96701 | — |
| The Cancer Center of Hawaii-Pali Momi | ‘Aiea | Hawaii | 96701 | — |
| Saint Alphonsus Cancer Care Center-Nampa | Nampa | Idaho | 83687 | — |
| Illinois CancerCare-Bloomington | Bloomington | Illinois | 61704 | — |
| Illinois CancerCare-Canton | Canton | Illinois | 61520 | — |
| Illinois CancerCare-Carthage | Carthage | Illinois | 62321 | — |
| Centralia Oncology Clinic | Centralia | Illinois | 62801 | — |
| Saint Mary's Hospital | Centralia | Illinois | 62801 | — |
| Jesse Brown Veterans Affairs Medical Center | Chicago | Illinois | 60612 | — |
| University of Illinois | Chicago | Illinois | 60612 | — |
| Carle at The Riverfront | Danville | Illinois | 61832 | — |
| Cancer Care Specialists of Illinois - Decatur | Decatur | Illinois | 62526 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Carle Physician Group-Effingham | Effingham | Illinois | 62401 | — |
| Crossroads Cancer Center | Effingham | Illinois | 62401 | — |
| Illinois CancerCare-Eureka | Eureka | Illinois | 61530 | — |
| Illinois CancerCare-Galesburg | Galesburg | Illinois | 61401 | — |
| Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois | 61443 | — |
| Illinois CancerCare-Macomb | Macomb | Illinois | 61455 | — |
| Carle Physician Group-Mattoon/Charleston | Mattoon | Illinois | 61938 | — |
| Cancer Care Center of O'Fallon | O'Fallon | Illinois | 62269 | — |
| HSHS Saint Elizabeth's Hospital | O'Fallon | Illinois | 62269 | — |
| Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | 61350 | — |
| Illinois CancerCare-Pekin | Pekin | Illinois | 61554 | — |
| Illinois CancerCare-Peoria | Peoria | Illinois | 61615 | — |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61636 | — |
| Illinois CancerCare-Peru | Peru | Illinois | 61354 | — |
| Illinois CancerCare-Princeton | Princeton | Illinois | 61356 | — |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | — |
| Springfield Clinic | Springfield | Illinois | 62702 | — |
| Springfield Memorial Hospital | Springfield | Illinois | 62781 | — |
| Carle Cancer Center | Urbana | Illinois | 61801 | — |
| The Carle Foundation Hospital | Urbana | Illinois | 61801 | — |
| Illinois CancerCare - Washington | Washington | Illinois | 61571 | — |
| Mary Greeley Medical Center | Ames | Iowa | 50010 | — |
| McFarland Clinic - Ames | Ames | Iowa | 50010 | — |
| UI Health Care Mission Cancer and Blood - Ankeny Clinic | Ankeny | Iowa | 50023 | — |
| Mercy Cancer Center-West Lakes | Clive | Iowa | 50325 | — |
| UI Health Care Mission Cancer and Blood - West Des Moines Clinic | Clive | Iowa | 50325 | — |
| Greater Regional Medical Center | Creston | Iowa | 50801 | — |
| Iowa Methodist Medical Center | Des Moines | Iowa | 50309 | — |
| UI Health Care Mission Cancer and Blood - Des Moines Clinic | Des Moines | Iowa | 50309 | — |
| Broadlawns Medical Center | Des Moines | Iowa | 50314 | — |
| Mercy Medical Center - Des Moines | Des Moines | Iowa | 50314 | — |
| UI Health Care Mission Cancer and Blood - Laurel Clinic | Des Moines | Iowa | 50314 | — |
| Iowa Lutheran Hospital | Des Moines | Iowa | 50316 | — |
| UI Health Care Mission Cancer and Blood - Waukee Clinic | Waukee | Iowa | 50263 | — |
| Methodist West Hospital | West Des Moines | Iowa | 50266-7700 | — |
| Mercy Medical Center-West Lakes | West Des Moines | Iowa | 50266 | — |
| CommonSpirit Saint Joseph Hospital - Lexington | Lexington | Kentucky | 40504 | — |
| Saint Joseph Radiation Oncology Resource Center | Lexington | Kentucky | 40504 | — |
| CommonSpirit Saint Joseph Medical Center - East Lexington | Lexington | Kentucky | 40509 | — |
| Beverly Hospital | Beverly | Massachusetts | 01915 | — |
| Lahey Clinic | Burlington | Massachusetts | 01805 | — |
| Addison Gilbert Hospital | Gloucester | Massachusetts | 01930 | — |
| Lahey Clinic Peabody | Peabody | Massachusetts | 01960 | — |
| Beth Israel Deaconess Medical Center/Winchester Center for Cancer Care | Winchester | Massachusetts | 01890 | — |
| Henry Ford Health Providence Novi Hospital | Novi | Michigan | 48374 | — |
| Henry Ford Health Providence Southfield Hospital | Southfield | Michigan | 48075 | — |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | — |
| Health Partners Inc | Minneapolis | Minnesota | 55454 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| Lakeview Hospital | Stillwater | Minnesota | 55082 | — |
| Baptist Memorial Hospital and Cancer Center-Desoto | Southhaven | Mississippi | 38671 | — |
| Saint Francis Medical Center | Cape Girardeau | Missouri | 63703 | — |
| Parkland Health Center - Farmington | Farmington | Missouri | 63640 | — |
| Mercy Clinic-Rolla-Cancer and Hematology | Rolla | Missouri | 65401 | — |
| Phelps Health Delbert Day Cancer Institute | Rolla | Missouri | 65401 | — |
| Sainte Genevieve County Memorial Hospital | Sainte Genevieve | Missouri | 63670 | — |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | — |
| Missouri Baptist Medical Center | St Louis | Missouri | 63131 | — |
| Missouri Baptist Sullivan Hospital | Sullivan | Missouri | 63080 | — |
| Bozeman Health Deaconess Hospital | Bozeman | Montana | 59715 | — |
| Benefis Sletten Cancer Institute | Great Falls | Montana | 59405 | — |
| Logan Health Medical Center | Kalispell | Montana | 59901 | — |
| University of New Mexico Cancer Center | Albuquerque | New Mexico | 87106 | — |
| Montefiore Medical Center-Einstein Campus | The Bronx | New York | 10461 | — |
| Montefiore Medical Center-Weiler Hospital | The Bronx | New York | 10461 | — |
| Montefiore Medical Center - Moses Campus | The Bronx | New York | 10467 | — |
| Dayton Physicians LLC-Miami Valley South | Centerville | Ohio | 45459 | — |
| Miami Valley Hospital South | Centerville | Ohio | 45459 | — |
| Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| Premier Blood and Cancer Center | Dayton | Ohio | 45409 | — |
| Dayton Physician LLC - Englewood | Dayton | Ohio | 45415 | — |
| Miami Valley Hospital North | Dayton | Ohio | 45415 | — |
| Atrium Medical Center-Middletown Regional Hospital | Franklin | Ohio | 45005-1066 | — |
| Miami Valley Cancer Care and Infusion | Greenville | Ohio | 45331 | — |
| Dayton Physicians LLC - Troy | Troy | Ohio | 45373 | — |
| Upper Valley Medical Center | Troy | Ohio | 45373 | — |
| Cancer Centers of Southwest Oklahoma Research | Lawton | Oklahoma | 73505 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Clackamas Radiation Oncology Center | Clackamas | Oregon | 97015 | — |
| Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Providence Saint Vincent Medical Center | Portland | Oregon | 97225 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| UPMC Hillman Cancer Center Erie | Erie | Pennsylvania | 16505 | — |
| UPMC Cancer Center at UPMC Horizon | Farrell | Pennsylvania | 16121 | — |
| UPMC Cancer Centers - Arnold Palmer Pavilion | Greensburg | Pennsylvania | 15601 | — |
| UPMC Hillman Cancer Center in Greenville/UPMC Horizon | Greenville | Pennsylvania | 16125 | — |
| UPMC Cancer Center - Monroeville | Monroeville | Pennsylvania | 15146 | — |
| UPMC Hillman Cancer Center - Monroeville | Monroeville | Pennsylvania | 15146 | — |
| UPMC Hillman Cancer Center - New Castle | New Castle | Pennsylvania | 16105 | — |
| UPMC-Saint Margaret | Pittsburgh | Pennsylvania | 15215 | — |
| UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | — |
| UPMC-Shadyside Hospital | Pittsburgh | Pennsylvania | 15232 | — |
| UPMC-Passavant Hospital | Pittsburgh | Pennsylvania | 15237 | — |
| UPMC-Saint Clair Hospital Cancer Center | Pittsburgh | Pennsylvania | 15243 | — |
| UPMC Cancer Center at UPMC Northwest | Seneca | Pennsylvania | 16346 | — |
| UPMC Cancer Center-Washington | Washington | Pennsylvania | 15301 | — |
| UPMC Washington Hospital Radiation Oncology | Washington | Pennsylvania | 15301 | — |
| Baptist Memorial Hospital and Cancer Center-Collierville | Collierville | Tennessee | 38017 | — |
| Baptist Memorial Hospital and Cancer Center-Memphis | Memphis | Tennessee | 38120 | — |
| Parkland Memorial Hospital | Dallas | Texas | 75235 | — |
| UT Southwestern Simmons Cancer Center - RedBird | Dallas | Texas | 75237 | — |
| UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas | 75390 | — |
| UT Southwestern/Simmons Cancer Center-Fort Worth | Fort Worth | Texas | 76104 | — |
| UT Southwestern Clinical Center at Richardson/Plano | Richardson | Texas | 75080 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| Swedish Medical Center-Ballard Campus | Seattle | Washington | 98107 | — |
| Swedish Medical Center-Cherry Hill | Seattle | Washington | 98122-5711 | — |
| Swedish Medical Center-First Hill | Seattle | Washington | 98122 | — |
| Ascension Northeast Wisconsin-Saint Elizabeth Cancer Center-Appleton | Appleton | Wisconsin | 54915 | — |
| Ascension Southeast Wisconsin Hospital-Elmbrook Campus-Brookfield | Brookfield | Wisconsin | 53045 | — |
| Ascension Calumet Hospital-Chilton | Chilton | Wisconsin | 53014 | — |
| Marshfield Medical Center-EC Cancer Center | Eau Claire | Wisconsin | 54701 | — |
| Ascension Southeast Wisconsin Hospital - Franklin | Franklin | Wisconsin | 53132 | — |
| Reiman Cancer Center-Ascension Wisconsin Health Center-Rawson | Franklin | Wisconsin | 53132 | — |
| Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | 54449 | — |
| Ascension Columbia Saint Mary's Hospital-Ozaukee Campus-Mequon | Mequon | Wisconsin | 53097 | — |
| Ascension Southeast Wisconsin Hospital-Saint Joseph-Milwaukee | Milwaukee | Wisconsin | 53210 | — |
| Ascension Columbia Saint Mary's Hospital-Milwaukee Campus | Milwaukee | Wisconsin | 53211 | — |
| Ascension Saint Francis Hospital-Milwaukee | Milwaukee | Wisconsin | 53215 | — |
| Marshfield Medical Center - Minocqua | Minocqua | Wisconsin | 54548 | — |
| Cancer Center of Western Wisconsin | New Richmond | Wisconsin | 54017 | — |
| Ascension Northeast Wisconsin-Mercy Hospital-Oshkosh | Oshkosh | Wisconsin | 54904 | — |
| Ascension All Saints Hospital-Spring Street-Racine | Racine | Wisconsin | 53405 | — |
| Marshfield Medical Center-Rice Lake | Rice Lake | Wisconsin | 54868 | — |
| Marshfield Medical Center-River Region at Stevens Point | Stevens Point | Wisconsin | 54482 | — |
| Ascension Southeast Wisconsin Hospital-Mayfair Road-Wauwatosa | Wauwatosa | Wisconsin | 53226 | — |
| Marshfield Medical Center - Weston | Weston | Wisconsin | 54476 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04310020, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 23, 2026 · Synced Sep 14, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04310020 live on ClinicalTrials.gov.