Anti-VEGF Therapy for Acute Thyroid Eye Disease
Public ClinicalTrials.gov record NCT04311606. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Anti-VEGF Therapy for Acute Thyroid Eye Disease (AcTED Study)
Study identification
- NCT ID
- NCT04311606
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Massachusetts Eye and Ear Infirmary
- Other
- Enrollment
- 11 participants
Conditions and interventions
Conditions
Interventions
- Sub-tenon injection of hyaluronidase (HA) alone Drug
- Sub-tenon injection of hyaluronidase (HA) followed by a sub-tenon injection of aflibercept Drug
- Sub-tenon injection of saline followed by a sub-tenon injection of aflibercept Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 1, 2020
- Primary completion
- Dec 16, 2024
- Completion
- Dec 16, 2024
- Last update posted
- Dec 30, 2025
2020 – 2024
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mass Eye and Ear | Boston | Massachusetts | 02114 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04311606, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 30, 2025 · Synced May 17, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04311606 live on ClinicalTrials.gov.