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Not listed Not applicable Interventional Accepts healthy volunteers

Transitioning to a Valve -Gated Intrathecal Drug Delivery System

ClinicalTrials.gov ID: NCT04312685

Public ClinicalTrials.gov record NCT04312685. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 11:29 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Transitioning to a Valve -Gated Intrathecal Drug Delivery System (IDDS): An Open-Label, Non-Randomized, Single-Blind, Multi-Center Study

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is designed to explore if the valve-gated pump requires less drug to manage subject pain than the prior standard peristaltic pump in the same subject. The newly implanted valve-gated pump will be programmed to deliver a minimum dose reduction of 20% of the same medication that was delivered in the peristaltic pump prior to explant. The drug therapy will be evaluated and pain scores will be evaluated over time (3 refill cycles prospectively for the valve-gated pump and 6 months retrospectively for the peristaltic pump).

Study identification

NCT ID
NCT04312685
Recruitment status
Not listed
Study type
Interventional
Phase
Not applicable
Lead sponsor
Bux, Anjum, MD
Other
Enrollment
120 participants

Conditions and interventions

Eligibility (public fields only)

Age range
21 Years and older
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 26, 2020
Primary completion
Mar 31, 2023
Completion
Nov 29, 2023
Last update posted
Jul 6, 2021

2020 – 2023

United States locations

U.S. sites
8
U.S. states
8
U.S. cities
8
Facility City State ZIP Site status
Pain and Spine Specialists Idaho Falls Idaho 83404
Crimson Pain Management Overland Park Kansas 66209
Bux Pain Management Lexington Kentucky 40509
Aust Interventional Pain Slidell Louisiana 70458
Michigan Head & Spine Institute Southfield Michigan 48034
National Spine & Pain Center Turnersville New Jersey 08012
The Spine Center at Ridgeway Rochester New York 14626
Consultants in Pain Management Chattanooga Tennessee 37421

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04312685, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 6, 2021 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04312685 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →