Trial Evaluating the Efficacy and Safety of Oral Vadadustat Once Daily (QD) and Three Times Weekly (TIW) for the Maintenance Treatment of Anemia in Hemodialysis Subjects Converting From Erythropoiesis-Stimulating Agents (ESAs)
Public ClinicalTrials.gov record NCT04313153. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 3b, Randomized, Open-label, Active-controlled Trial Evaluating the Efficacy and Safety of Oral Vadadustat Once Daily (QD) and Three Times Weekly (TIW) for the Maintenance Treatment of Anemia in Hemodialysis Subjects Converting From Erythropoiesis-Stimulating Agents (ESAs)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This trial will be conducted to demonstrate the efficacy and safety of vadadustat compared to darbepoetin alfa for the maintenance treatment of anemia in hemodialysis participants after conversion from current erythropoiesis-stimulating agent (ESA) therapy.
Study identification
- NCT ID
- NCT04313153
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 319 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 27, 2020 (Actual)
- Primary completion
- Nov 26, 2021 (Actual)
- Completion
- Jun 22, 2022 (Actual)
- Last update posted
- May 22, 2025
2020 – 2022
United States locations
- U.S. sites
- 39
- U.S. states
- 16
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Chula Vista | California | 91910 | — |
| Research Site | Granada Hills | California | 91344 | — |
| Research Site | Los Angeles | California | 90022 | — |
| Research Site | Lynwood | California | 90262 | — |
| Research Site | Northridge | California | 91324 | — |
| Research Site | San Dimas | California | 91773 | — |
| Research Site | Whittier | California | 90603 | — |
| Research Site | Denver | Colorado | 80230 | — |
| Research Site | Middlebury | Connecticut | 06762 | — |
| Research Site | Coral Gables | Florida | 33134 | — |
| Research Site | Tampa | Florida | 33614 | — |
| Research Site | Winter Park | Florida | 32789 | — |
| Research Site | Pontiac | Michigan | 48341 | — |
| Research Site | Roseville | Michigan | 48066 | — |
| Research Site | Minneapolis | Minnesota | 55404 | — |
| Research Site | Brookhaven | Mississippi | 39601 | — |
| Research Site | Tupelo | Mississippi | 38801 | — |
| Research Site | Kansas City | Missouri | 64111 | — |
| Research Site | St Louis | Missouri | 63136 | — |
| Research Site | Las Vegas | Nevada | 89128 | — |
| Research Site | Albuquerque | New Mexico | 87109 | — |
| Research Site | Durham | North Carolina | 27704 | — |
| Research Site | Kinston | North Carolina | 28504 | — |
| Research Site | New Bern | North Carolina | 28562 | — |
| Research Site | Bethlehem | Pennsylvania | 18017 | — |
| Research Site | Orangeburg | South Carolina | 29118 | — |
| Research Site | Chattanooga | Tennessee | 37404 | — |
| Research Site | Knoxville | Tennessee | 37920 | — |
| Research Site | Knoxville | Tennessee | 37923 | — |
| Research Site | Austin | Texas | 78751 | — |
| Research Site | Austin | Texas | 78758 | — |
| Research Site | El Paso | Texas | 79902 | — |
| Research Site | Houston | Texas | 77004 | — |
| Research Site | Houston | Texas | 77099 | — |
| Research Site | McAllen | Texas | 78503 | — |
| Research Site | San Antonio | Texas | 78204 | — |
| Research Site | San Antonio | Texas | 78212 | — |
| Research Site | San Antonio | Texas | 78229 | — |
| Research Site | Hampton | Virginia | 23666 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04313153, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 22, 2025 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04313153 live on ClinicalTrials.gov.