A Study to Evaluate the Safety and Efficacy of Tocilizumab in Patients With Severe COVID-19 Pneumonia
Public ClinicalTrials.gov record NCT04320615. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Safety and Efficacy of Tocilizumab in Patients With Severe COVID-19 Pneumonia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the efficacy, safety, pharmacodynamics, and pharmacokinetics of tocilizumab (TCZ) compared with a matching placebo in combination with standard of care (SOC) in hospitalized patients with severe COVID-19 pneumonia.
Study identification
- NCT ID
- NCT04320615
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 452 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2, 2020
- Primary completion
- Jun 23, 2020
- Completion
- Jul 27, 2020
- Last update posted
- Jun 29, 2021
2020
United States locations
- U.S. sites
- 23
- U.S. states
- 15
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of California San Diego | La Jolla | California | 92093 | — |
| eStudySite | La Mesa | California | 91942 | — |
| David Geffen School of Medicine UCLA | Los Angeles | California | 90095 | — |
| Stanford University | Stanford | California | 94305 | — |
| Denver Health Medical Center | Denver | Colorado | 80204 | — |
| University of Miami Miller School of Medicine | Miami | Florida | 33136 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Ochsner Clinic Foundation | Baton Rouge | Louisiana | 70809 | — |
| Baystate Health System | Springfield | Massachusetts | 01199 | — |
| Mayo Clinic - PPDS | Rochester | Minnesota | 55905 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Robert Wood Johnson University Hospital/Rutgers | New Brunswick | New Jersey | 08901 | — |
| James J Peters Veterans Administration Medical Center - NAVREF | The Bronx | New York | 10468 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Cleveland Clinic Foundation; Pulmonary, Allergy & Critical Care Medicine | Cleveland | Ohio | 44195 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Baylor St. Luke's Medical Center | Houston | Texas | 77030 | — |
| Ben Taub General Hospital - HCHD | Houston | Texas | 77030 | — |
| Intermountain LDS Hospital | Salt Lake City | Utah | 84143 | — |
| Intermountain Medical Group | St. George | Utah | 84770 | — |
| Evergreen Health Infectious Disease | Kirkland | Washington | 98034 | — |
| Swedish Hospital Medical Center | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 39 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04320615, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 29, 2021 · Synced Sep 25, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04320615 live on ClinicalTrials.gov.