A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Esophagitis
Public ClinicalTrials.gov record NCT04322708. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2/3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Lirentelimab (AK002) in Adult and Adolescent Patients With Active Eosinophilic Esophagitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 2/3, multi-center, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of lirentelimab (AK002) given monthly for 6 doses in adult and adolescent patients with active eosinophilic esophagitis. Subjects who complete the randomized, double-blind, placebo-controlled treatment may have the option to receive 6 doses of open-label lirentelimab (AK002) through the OLE Period of the study.
Study identification
- NCT ID
- NCT04322708
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 277 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 6, 2020 (Actual)
- Primary completion
- Jun 4, 2021 (Actual)
- Completion
- Jan 18, 2022 (Actual)
- Last update posted
- Jan 2, 2024
2020 – 2022
United States locations
- U.S. sites
- 73
- U.S. states
- 29
- U.S. cities
- 65
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Allakos Investigational Site | Birmingham | Alabama | 35209 | — |
| Allakos Investigational Site | Huntsville | Alabama | 38801 | — |
| Allakos Investigational Site | Gilbert | Arizona | 85234 | — |
| Allakos Investigational Site | Phoenix | Arizona | 85016 | — |
| Allakos Investigational Site | Phoenix | Arizona | 85021 | — |
| Allakos Investigational Site | Scottsdale | Arizona | 85251 | — |
| Allakos Investigational Site | Little Rock | Arkansas | 72205 | — |
| Allakos Investigational Site | La Jolla | California | 92037 | — |
| Allakos Investigational Site | Los Angeles | California | 90025 | — |
| Allakos Investigational Site | Oakland | California | 94612 | — |
| Allakos Investigational Site | Santa Monica | California | 90404 | — |
| Allakos Investigational Site | Tustin | California | 92780 | — |
| Allakos Investigational Site | Ventura | California | 93003 | — |
| Allakos Investigational Site | Walnut Creek | California | 94598 | — |
| Allakos Investigational Site | Aurora | Colorado | 80045 | — |
| Allakos Investigational Site | Centennial | Colorado | 80112 | — |
| Allakos Investigational Site | Brandon | Florida | 33511 | — |
| Allakos Investigational Site | Edgewater | Florida | 32132 | — |
| Allakos Investigational Site | Jacksonville | Florida | 32256 | — |
| Allakos Investigational Site | Miami | Florida | 33176 | — |
| Allakos Investigational Site | Orlando | Florida | 32803 | — |
| Allakos Investigational Site | Orlando | Florida | 32806 | — |
| Allakos Investigational Site | Tampa | Florida | 33603 | — |
| Allakos Investigational Site | Tampa | Florida | 33615 | — |
| Allakos Investigational Site | Atlanta | Georgia | 30342 | — |
| Allakos Investigational Site | Columbus | Georgia | 31904 | — |
| Allakos Investigational Site | Chicago | Illinois | 60611 | — |
| Allakos Investigational Site | Indianapolis | Indiana | 46202 | — |
| Allakos Investigational Site | Iowa City | Iowa | 52242 | — |
| Allakos Investigational Site | Lexington | Kentucky | 40503 | — |
| Allakos Investigational Site | Crowley | Louisiana | 70526 | — |
| Allakos Investigational Site | Chevy Chase | Maryland | 20815 | — |
| Allakos Investigational Site | Boston | Massachusetts | 02111 | — |
| Allakos Investigational Site | Boston | Massachusetts | 02115 | — |
| Allakos Investigational Site | Boston | Massachusetts | 02215 | — |
| Allakos Investigational Site | Ann Arbor | Michigan | 48109 | — |
| Allakos Investigational Site | Troy | Michigan | 48098 | — |
| Allakos Investigational Site | Kansas City | Missouri | 64108 | — |
| Allakos Investigational Site | Kalispell | Montana | 59901 | — |
| Allakos Investigational Site | Las Vegas | Nevada | 89106 | — |
| Allakos Investigational Site | Reno | Nevada | 89511 | — |
| Allakos Investigational Site | Great Neck | New York | 11021 | — |
| Allakos Investigational Site | New York | New York | 10029 | — |
| Allakos Investigational Site | Asheville | North Carolina | 28801 | — |
| Allakos Investigational Site | Chapel Hill | North Carolina | 27599 | — |
| Allakos Investigational Site | Charlotte | North Carolina | 28210 | — |
| Allakos Investigational Site | Charlotte | North Carolina | 28277 | — |
| Allakos Investigational Site | Durham | North Carolina | 27710 | — |
| Allakos Investigational Site | High Point | North Carolina | 27262 | — |
| Allakos Investigational Site | Rocky Mount | North Carolina | 27804 | — |
| Allakos Investigational Site | Akron | Ohio | 44302 | — |
| Allakos Investigational Site | Cincinnati | Ohio | 45229 | — |
| Allakos Investigational Site | Cincinnati | Ohio | 45231 | — |
| Allakos Investigational Site | Cleveland | Ohio | 44106 | — |
| Allakos Investigational Site | Dayton | Ohio | 45415 | — |
| Allakos Investigational Site | Mentor | Ohio | 44060 | — |
| Allakos Investigational Site | Oklahoma City | Oklahoma | 73112 | — |
| Allakos Investigational Site | Danville | Pennsylvania | 17822 | — |
| Allakos Investigational Site | Philadelphia | Pennsylvania | 19104 | — |
| Allakos Investigational Site | Greenville | South Carolina | 29615 | — |
| Allakos Investigational Site | Chattanooga | Tennessee | 37421 | — |
| Allakos Investigational Site | Hixson | Tennessee | 37343 | — |
| Allakos Investigational Site | Nashville | Tennessee | 37212 | — |
| Allakos Investigational Site | Austin | Texas | 78704 | — |
| Allakos Investigational Site | Garland | Texas | 75044 | — |
| Allakos Investigational Site | San Antonio | Texas | 78229 | — |
| Allakos Investigational Site | Ogden | Utah | 84405 | — |
| Allakos Investigational Site | Riverton | Utah | 84065 | — |
| Allakos Investigational Site | Salt Lake City | Utah | 84132 | — |
| Allakos Investigational Site | Sandy City | Utah | 84092 | — |
| Allakos Investigational Site | Leesburg | Virginia | 20176 | — |
| Allakos Investigational Site | Seattle | Washington | 98105 | — |
| Allakos Investigational Site | Seattle | Washington | 98115 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04322708, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 2, 2024 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04322708 live on ClinicalTrials.gov.