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Completed Phase 3 Interventional Accepts healthy volunteers Results available

Healthcare Worker Exposure Response and Outcomes of Hydroxychloroquine

ClinicalTrials.gov ID: NCT04334148

Public ClinicalTrials.gov record NCT04334148. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 10:40 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Healthcare Worker Exposure Response and Outcomes of Hydroxychloroquine Trial (HERO-HCQ Trial)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a double blind, placebo controlled study in approximately 2,000 health care workers at risk for being exposed to COVID-19. Eligible participants will be randomly assigned (1:1) to either treatment group (HCQ) or placebo in a double-blind fashion. Course of treatment is 30 days.

Study identification

NCT ID
NCT04334148
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Adrian Hernandez
Other
Enrollment
1,360 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 22, 2020 (Actual)
Primary completion
Dec 10, 2020 (Actual)
Completion
Jan 9, 2021 (Actual)
Last update posted
Oct 12, 2021

2020 – 2021

United States locations

U.S. sites
34
U.S. states
19
U.S. cities
30
Facility City State ZIP Site status
Children's Hospital Colorado/University of Colorado Denver Aurora Colorado 80045 —
University of Florida Gainesville Florida 32610 —
University of Florida Jacksonville Jacksonville Florida 32206 —
University of Florida Health Central Florida Leesburg Florida 34748 —
University of Miami Florida Miami Florida 33136 —
Advent Health Orlando Florida 32804 —
University of South Florida Tampa Florida 33606 —
Northwestern Medicine Chicago Illinois 60611 —
Rush University Chicago Illinois 60612 —
University of Iowa Iowa City Iowa 52242 —
University of Kansas Medical Center Kansas City Kansas 66160 —
University Medical Center New Orleans New Orleans Louisiana 70112 —
Ochsner Clinic Foundation New Orleans Louisiana 70121 —
Johns Hopkins Baltimore Maryland 21287 —
University of Michigan Ann Arbor Michigan 48109 —
Allina Health Minneapolis Minnesota 55404 —
Mayo Clinic Hospital Rochester Rochester Minnesota 55905 —
University of Missouri-Columbia Columbia Missouri 65212 —
University of Nebraska Medical Center Omaha Nebraska 68198 —
Hospital for Special Surgery New York New York 10021 —
Columbia University, Irving Medical Center New York New York 10032 —
Weill Cornell Medicine New York New York 10065 —
University of North Carolina at Chapel Hill Chapel Hill North Carolina 27599 —
Duke University Medical Center Durham North Carolina 27710 —
Wake Forest Baptist Health Sciences Winston-Salem North Carolina 27157 —
The Ohio State University Wexner Medical Center Columbus Ohio 43210 —
Temple University Hospital Philadelphia Pennsylvania 19140 —
University of Pittsburgh School of Medicine Pittsburgh Pennsylvania 15213 —
Clinical Trials Center of Middle Tennessee Franklin Tennessee 37067 —
Vanderbilt University Medical Center Nashville Tennessee 37232 —
University of Texas Southwestern Medical Center Dallas Texas 75390 —
Baylor Scott & White Medical Center-Temple Temple Texas 76504 —
Seattle Children's Hospital Seattle Washington 98105 —
Marshfield Clinic Health System Marshfield Wisconsin 54449 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04334148, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 12, 2021 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04334148 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →