Evaluate the Efficacy & Safety of Leronlimab in Patients With Severe or Critical COVID-19
Public ClinicalTrials.gov record NCT04347239. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b/3, Randomized, Double Blind, Placebo Controlled, Adaptive Design Study to Evaluate the Efficacy and Safety of Leronlimab for Patients With Severe or Critical Coronavirus Disease 2019 (COVID-19)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study was assess the safety and efficacy of leronlimab (PRO 140) administered as weekly subcutaneous injection in subjects with severe or critical COVID-19 disease.
Study identification
- NCT ID
- NCT04347239
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 484 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 16, 2020 (Actual)
- Primary completion
- Oct 24, 2021 (Actual)
- Completion
- Jun 15, 2022 (Actual)
- Last update posted
- Oct 15, 2025
2020 – 2022
United States locations
- U.S. sites
- 18
- U.S. states
- 11
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Advanced Cardiovascular, LLC | Alexander City | Alabama | 35010 | — |
| St. Jude Medical Center | Fullerton | California | 92835 | — |
| UCLA | Los Angeles | California | 90095 | — |
| James A. Haley Veterans' Hospital | Tampa | Florida | 33612 | — |
| Center for Advanced Research & Education (CARE) | Gainesville | Georgia | 30501 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| St. Barnabas | Livingston | New Jersey | 07052 | — |
| Atlantic Health System Hospital | Morristown | New Jersey | 07962-1905 | — |
| Holy Name Medical Center | Teaneck | New Jersey | 07666 | — |
| New York Community Hospital of Brooklyn | Brooklyn | New York | 11229 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Novant Health | Winston-Salem | North Carolina | 27103 | — |
| Ohio Health | Columbus | Ohio | 43215 | — |
| Good Samaritan Hospital Corvallis | Corvallis | Oregon | 97330 | — |
| Oregon Health and Sciences University | Portland | Oregon | 97239 | — |
| Baylor Scott & White Research Institute | Dallas | Texas | 75204 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| University of Texas | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04347239, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 15, 2025 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04347239 live on ClinicalTrials.gov.