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Completed Phase 2 Interventional Results available

Evaluation of Activity and Safety of Oral Selinexor in Participants With Severe COVID-19 Infection

ClinicalTrials.gov ID: NCT04349098

Public ClinicalTrials.gov record NCT04349098. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 6:06 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Randomized Single-Blind Study to Evaluate the Activity and Safety of Low Dose Oral Selinexor (KPT-330) in Patients With Severe COVID-19 Infection

Study identification

NCT ID
NCT04349098
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Karyopharm Therapeutics Inc
Industry
Enrollment
190 participants

Conditions and interventions

Interventions

  • Selinexor Drug
  • Placebo Other

Drug · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 16, 2020
Primary completion
Oct 4, 2020
Completion
Oct 4, 2020
Last update posted
Jan 19, 2023

2020

United States locations

U.S. sites
20
U.S. states
13
U.S. cities
18
Facility City State ZIP Site status
UCLA Los Angeles California 90095
Kaiser Permanente Oakland Oakland California 94612
UC Davis Health Sacramento California 95817
Kaiser Permanente Sacramento Sacramento California 95825
Kaiser Permanente San Francisco San Francisco California 94115
Miami Cancer Institute at Baptist Health Miami Florida 33176
Emory University Atlanta Georgia 30322
Advocate Christ Medical Center Oak Lawn Illinois 60453
University of Kansas Medical Center Kansas City Kansas 64113
Norton Healthcare Louisville Kentucky 40202
Boston Medical Center Boston Massachusetts 02118
Karmanos Detroit Michigan 48201
Michigan Center of Medical Research Farmington Hills Michigan 48336
Michigan Center of Medical Research Royal Oak Michigan 48073
Columbia University New York New York 10032
Weill Cornell Medical College New York New York 10065
Levine Cancer Institute-Atrium Health University City Charlotte North Carolina 28204
Lehigh Valley Hospital Allentown Pennsylvania 18103
Baylor Scott & White Dallas Dallas Texas 75201
MultiCare Institute for Research & Innovation (Puget Sound) Tacoma Washington 98405

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 13 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04349098, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 19, 2023 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04349098 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →