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Completed Phase 3 Interventional Results available

Trial to Evaluate the Efficacy and Safety of Nitazoxanide (NTZ) for Pre- and Post Exposure Prophylaxis of COVID-19 and Other Viral Respiratory Illnesses (VRI) in Healthcare Workers and Others at Increased Risk of SARS-CoV-2 Infection

ClinicalTrials.gov ID: NCT04359680

Public ClinicalTrials.gov record NCT04359680. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 4:56 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo Controlled Trial to Evaluate the Efficacy and Safety of Nitazoxanide (NTZ) for Pre- and Post Exposure Prophylaxis of COVID-19 and Other Viral Respiratory Illnesses (VRI) in Healthcare Workers and Others at Increased Risk of SARS-CoV-2 Infection

Study identification

NCT ID
NCT04359680
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Romark Laboratories L.C.
Industry
Enrollment
1,407 participants

Conditions and interventions

Interventions

  • Nitazoxanide Drug
  • Placebo Drug
  • Vitamin Super B-Complex Dietary Supplement

Drug · Dietary Supplement

Eligibility (public fields only)

Age range
18 Years to 120 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 12, 2020
Primary completion
Apr 6, 2021
Completion
Apr 6, 2021
Last update posted
Jun 25, 2024

2020 – 2021

United States locations

U.S. sites
26
U.S. states
10
U.S. cities
24
Facility City State ZIP Site status
HealthStar Research LLC Hot Springs Arkansas 71913
So Cal Clinical Research Huntington Beach California 92647
Long Beach Clinical Trials, LLC Long Beach California 90806
Meris Clinical Research Brandon Florida 33511
Invesclinica US LLC Fort Lauderdale Florida 33308
The Chappel Group Research Kissimmee Florida 34744
New Horizon Research Center Miami Florida 33165
Clinical Neuroscience Solutions, Inc. Orlando Florida 32801
DMI Research Pinellas Park Florida 33782
Tampa General Hospital Tampa Florida 33606
Chicago Clinical Research Institute, Inc. Chicago Illinois 60607
Chicago Medical Research Institute, Inc. Chicago Illinois 60607
Quad Clinical Research Chicago Illinois 60643
Chicago Medical Research, LLC Hazel Crest Illinois 60429
Centex Studies, Inc. Lake Charles Louisiana 70601
Vida Clinical Studies Dearborn Michigan 48124
Beacom Family Health Connection Fremont Nebraska 68025
North Jersey Community Research Initiative Newark New Jersey 07103
Integrative Clinical Trials LLC Brooklyn New York 11229
The New York Center for Travel and Tropical Medicine New York New York 10022
RH Medical Urgent Care Professional PLLC The Bronx New York 10456
Centex Studies, Inc. Houston Texas 77058
SMS Clinical Research LLC Mesquite Texas 75149
LinQ Research LLC Pearland Texas 77584
Rio Grande Valley Clinical Research Institute Pharr Texas 78577
BFHC Research San Antonio Texas 78249

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04359680, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 25, 2024 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04359680 live on ClinicalTrials.gov.

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